Human Oncology & Pathogenesis Program

The Nikolaus Schultz Lab

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Research

Nikolaus Schultz
Nikolaus Schultz, PhD
Head of Knowledge Systems, Marie-Josée & Henry R. Kravis Center for Molecular Oncology

Associate Professor

The Schultz lab focuses on identifying the genomic alterations that underlie different types of cancer. By applying existing and novel computational methods to large scale cancer genomics data sets, the lab aims to better understand the complex mechanisms at the gene and at the pathway level that drive tumor initiation, progression and response to therapy, with the ultimate goal of identifying targeted therapeutic options for cancer patients. A new focus of the lab is the systematic extraction and standardization of clinical data elements from electronic health records. The lab is also involved in collaborative large-scale projects such as The Cancer Genome Atlas (TCGA),  AACR Project GENIE, and the Human Tumor Atlas (HTAN). The group also has a strong interest in enabling discoveries by developing novel computational methods and databases that help bridge the divide between computer scientists on one side and clinicians and researchers on the other. Examples of these include the cBioPortal for Cancer Genomics, a popular resource for the visualization and analysis of cancer genomics data, and OncoKB, a precision oncology knowledgebase.

Nikolaus Schultz Lab

Publications

Chakravarty D, Gao J, Phillips SM, Kundra R, et al. OncoKB: A Precision Oncology Knowledge Base. JCO Precis Oncol. 2017 Jul.

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People

Nikolaus Schultz

Nikolaus Schultz, PhD

Head of Knowledge Systems, Marie-Josée & Henry R. Kravis Center for Molecular Oncology

Associate Professor

  • Cancer biologist Nikolaus Schultz uses computational tools to study the diversity of genomic alterations underlying different cancer types.
  • PhD, Freie Universitat Berlin
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Members

Adam Abeshouse
Adam Abeshouse

Bioinformatics Software Engineer I

Debyani Chakravarty, PhD
Debyani Chakravarty

Lead Scientist, OncoKB

Walid Chatila
Walid Chatila

Graduate Student

Ino de Bruijn, Bioinformatics Engineer
Ino de Bruijn

Bioinformatics Engineer

Christopher Fong, Research Scholar
Christopher Fong

Research Scholar

Jianjiong Gao, PhD
Jianjiong Gao

Lead Scientist, Knowledge Systems

Benjamin Gross, MS
Benjamin Gross

Bioinformatics Software Engineer Lead I

Ritika Kundra, MS
Ritika Kundra

Data Curator, OncoKB

Konnor La
Konnor La

Graduate Student

Aaron Lisman
Aaron Lisman

Bioinformatics Software Engineer, Lead

Subhiksha Nandakumar
Subhiksha Nandakumar

Bioinformatics Engineer

Bastien Nguyen
Bastien Nguyen

Research Scholar

Moriah Nissan
Moriah Nissan

Scientific Editor, OncoKB

Angelica  Ochoa
Angelica Ochoa

Bioinformatics Software Engineer II

Sarah  Phillips
Sarah Phillips

Scientific Editor, OncoKB

Arjun Raj Rajanna
Arjun Raj Rajanna

Bioinformatics Engineer

Julia Rudolph
Julia Rudolph

Associate Director, CRC Initiatives

Francisco  Sanchez-Vega
Francisco Sanchez-Vega

Research Scholar

Robert Sheridan
Robert Sheridan

Software Engineer

Hongyu Shi
Hongyu Shi
Jing Su
Jing Su

Bioinformatics Software Engineer I

Selcuk  Onur  Sumer
Selcuk Onur Sumer

Software Engineer

Yichao Sun, MS
Yichao Sun

Bioinformatics Software Engineer

Henry Walch
Henry Walch

Bioinformatics Software Engineer

Avery Wang

Bioinformatics Engineer I

Hongxin Zhang
Hongxin Zhang

Bioinformatics Software Engineer

Lab Alumni
Joshua Armenia
Joshua Armenia

Research Fellow

Hsiao-Wei  (Annice)  Chen
Hsiao-Wei (Annice) Chen

Data Curator

Frederick Criscuolo

Computational Engineer

Zachary  Heins
Zachary Heins

Bioinformatics Engineer

Dong Li

Computational Engineer

Eduard Reznik

Manager, Biocomputing

Jiaojiao  Wang
Jiaojiao Wang

Bioinformatics Software Engineer I

Qingguo Wang
Qingguo Wang

Bioinformatics Software Engineer

Lab Affilations

Achievements

  • Geoffrey Beene Junior Faculty Chair (2019)
  • Stupski Prize in Prostate Cancer Computational Oncology (2015)
  • Young Investigator Award, Prostate Cancer Foundation (2014)
  • Josie Robertson Investigator Award, Robertson Foundation (2013)

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Nikolaus Schultz discloses the following relationships and financial interests:

  • American Association for Cancer Research
    Provision of Services (uncompensated)
  • Bladder Cancer Advocacy Network (BCAN)
    Provision of Services (uncompensated)
  • Genome Institute of Singapore
    Provision of Services (uncompensated)
  • Innovation in Cancer Informatics
    Provision of Services (uncompensated)

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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