The focus of the Berger laboratory is to characterize the spectrum of genetic mutations in human tumors in order to identify biomarkers of cancer progression and drug response.
Michael F. Berger, PhD
Associate Director, Marie-Josée & Henry R. Kravis Center for Molecular Oncology
Associate Professor
Research Focus
Researcher Michael Berger focuses on massively parallel sequencing of tumor DNA for biomarker discovery and clinical diagnostics.Education
PhD, Harvard UniversityLab Members
Maysun Hasan
Computational Biologist, CMO Technology Innovation
Brian Houck- Loomis
Manager, CMO Technology Innovation
Xiaohong Jing
Lab Manager, CMO Technology Innovation
Ian Johnson
Bioinformatics Engineer, CMO Technology Innovation
Fanli Meng
Research Assistant, CMO Technology Innovation
Juber Ahamad Patel
Computational Biologist, CMO Technology Innovation
Preethi Srinivasan
Graduate Student
Grittney Tam
Research Assistant
Peter Zheng
Bioinformatics Technician
Publications
- Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes. Coombs CC, Zehir A, Devlin SM, Kishtagari A, Syed A, Jonsson P, Hyman DM, Solit DB, Robson ME, Baselga J, Arcila ME, Ladanyi M, Tallman MS, Levine RL, Berger MF. Cell Stem Cell. 2017 Sep 7;21(3):374-382.e4. doi: 10.1016/j.stem.2017.07.010. Epub 2017 Aug 10.
- Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing. Mandelker D, Zhang L, Kemel Y, Stadler ZK, Joseph V, Zehir A, Pradhan N, Arnold A, Walsh MF, Li Y, Balakrishnan AR, Syed A, Prasad M, Nafa K, Carlo MI, Cadoo KA, Sheehan M, Fleischut MH, Salo-Mullen E, Trottier M, Lipkin SM, Lincoln A, Mukherjee S, Ravichandran V, Cambria R, Galle J, Abida W, Arcila ME, Benayed R, Shah R, Yu K, Bajorin DF, Coleman JA, Leach SD, Lowery MA, Garcia-Aguilar J, Kantoff PW, Sawyers CL, Dickler MN, Saltz L, Motzer RJ, O’Reilly EM, Scher HI, Baselga J, Klimstra DS1, Solit DB, Hyman DM, Berger MF, Ladanyi M, Robson ME, Offit K. JAMA. 2017 Sep 5;318(9):825-835. doi: 10.1001/jama.2017.11137.
