Memorial Hospital Research Laboratories

The Jonathan Peled Lab


Jonathan Peled
Jonathan Peled, MD, PhD

Assistant Professor

Cancer immunotherapy hold tremendous promise, but durable responses in most disease types are achieved in only a minority of patients. For example, allogeneic hematopoietic-cell transplantation (allo-HCT) is a curative treatment for hematological malignancies, but its success is limited by relapse, graft-vs-host disease (GVHD), or infection. We and others have established that GVHD severity and mortality risk after transplantation are in part dependent on the composition of the intestinal microbiota, yet the mechanisms by which this is mediated remain poorly understood. The Peled laboratory seeks to use human specimens and mouse models to understand how the gut microbiome and host immunity regulate one another and how these relationships might be manipulated to improve immunotherapy for patients with cancer.

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Research Projects


Peled JU et al. Microbiota as a predictor of mortality in allogeneic HCT. N Engl J Med. 2020 Feb 27;382(9):822-834. 

Stein-Thoeringer CK … Peled JU*, van den Brink MRM.* Lactose drives Enterococcus expansion to promote graft-versus-host disease. Science. 2019 Nov 29;366(6469):1143-1149.

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Jonathan Peled

Jonathan Peled, MD, PhD


Assistant Professor

  • The Peled lab focuses on cancer immunotherapy.
  • MD, PhD, Albert Einstein College of Medicine
[email protected]
Email Address
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Physician profile


Binita Febles
Binita Febles

Computational Biologist

Cindy Junes

Administrative Assistant

Madhumitha Rangesa

Senior Research Technician

Lab Affiliations


  • NHLBI K08
  • New Investigator Award from the American Society for Transplantation and Cellular Therapy
  • Career Development Award from the Parker Institute for Cancer Immunotherapy

Open Positions

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Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Jonathan Peled discloses the following relationships and financial interests:

  • CSL Behring
    Professional Services and Activities
  • Fred Hutchinson Cancer Research Center
    Professional Services and Activities
  • French National Research Agency
    Professional Services and Activities
  • Keio University
    Professional Services and Activities
  • MaaT Pharma
    Professional Services and Activities
  • Postbiotics Plus Research, LLC
    Equity; Professional Services and Activities (Uncompensated)
  • Seres Therapeutics
    Intellectual Property Rights
  • Tufts Medical Center
    Professional Services and Activities
  • Westchester Medical Center
    Professional Services and Activities

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.

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