Chemical Biology Program

The Daniel Bachovchin Lab

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Research

Daniel Bachovchin
Daniel Bachovchin, PhD


Associate Professor

The Bachovchin lab uses chemical and cell biology approaches to study important questions in innate immunity. We are particularly interested characterizing in the molecular mechanisms controlling the formation of inflammasomes, key components of the innate immune system that sense intracellular danger signals and trigger pyroptotic cell death. 

Publications

Chui, A.J*; Okondo, M.C.*; Rao, S.D.*; Gai, K.; Griswold, A.R.; Johnson, D.C.; Ball, D.P.; Taabazuing, C.Y.; Orth, E.L.; Vittimberga, B.A.; Bachovchin, D.A. # “N-terminal degradation activates the Nlrp1b inflammasome.” Science. 2019, 365, 82-85.

Griswold, A.R.; Cifani, P.; Rao, S.D.; Axelrod, A.J.; Miele, M.M.; Hendrickson, R.C.; Kensis, A.; Bachovchin, D.A. # “A chemical strategy for protease substrate profiling.” Cell Chem Biol. 2019, 26, 901-907.

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People

Daniel Bachovchin

Daniel Bachovchin, PhD



Associate Professor

  • Chemical biologist Daniel Bachovchin designs selective inhibitors to study enzymes and pathways in cancer and immune system signaling.
  • PhD, The Scripps Research Institute
bachovcd@mskcc.org
Email Address
Download CV
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Members

Samantha Phaggoo

Administrative Assistant

Daniel Ball, Research Fellow
Daniel Ball

Research Fellow

Abir Bhattacharjee
Abir Bhattacharjee

Research Fellow

Qifeng Chen
Qifeng Chen

Research Fellow

Andrew Griswold, Graduate Student
Andrew Griswold

Graduate Student

Jeff Chieh Hsiao
Jeff Chieh Hsiao

Graduate Student

Hsin-Che Huang

Graduate Student

Elizabeth Orth
Elizabeth Orth

Graduate Student

Sahana Rao, Graduate Student
Sahana Rao

Graduate Student

Cornelius  Taabazuing
Cornelius Taabazuing

Research Fellow

Alvin Wang
Alvin Wang

Research Technician

Qinghui Wang
Qinghui Wang

Research Fellow

Lab Alumni
Ashley  Chui
Ashley Chui

Graduate Student

Kuo Gai, Research Technician
Kuo Gai

Research Technician

Darren Johnson
Darren Johnson

Graduate Student

Marian Okondo
Marian Okondo

Research Technician

Lab Affiliations

Achievements

  • Josie Robertson Investigator (2015-2020)
  • Sloan Research Fellow in Chemistry (2018)
  • Stand Up to Cancer 2017 Innovative Research Grant Recipient (2017-2020)
  • Pew-Stewart Scholar for Cancer Research (2017-2021)
  • Pershing Square Sohn Prize for Young Innovators in Cancer Research (2018)
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  • California Breast Cancer Research Program Fellowship (2011-2012)
  • National Science Foundation Predoctoral Fellowship (2006-2007)

Lab News & Events

Upcoming event

Uncovering the Cryptic Activity of a Proteasome-Associated Deubiquitinase

This seminar will place at the ZRC auditorium and by Zoom webinar. 

Memorial Sloan Kettering Cancer Center
Zuckerman Research Center
417 East 68th Street
Room ZRC Auditorium
New York, NY 10065

Open Positions

Graduate Students

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Postdoctoral Fellows

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Get in Touch

Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Daniel Bachovchin discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2020 through disclosure submission in spring 2021). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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