My laboratory studies how mRNA elements that do not encode amino acids contribute to the regulation of biological complexity. We examine how 3′ untranslated regions (3′UTRs) regulate protein functions without affecting protein abundance. We also investigate the role of mRNAs as cytoplasmic organizers that enable subcellular compartmentalization required for the implementation of protein functions.
Christine Mayr, MD, PhD
Research FocusMolecular and cell biologist Christine Mayr studies how 3′UTRs regulate protein functions and how mRNAs contribute to cytoplasmic organization.
- MD, Free University Berlin
- PhD, Humboldt University Berlin
- Ma W, Mayr C. A membraneless organelle associated with the endoplasmic reticulum enables 3′UTR-mediated protein-protein interactions. Cell 175, 1492-1506 (2018).
- Berkovits BD, Mayr C. Alternative 3’UTRs act as scaffolds to regulate membrane protein localization. Nature 522, 363-367 (2015). Epub 2015 Apr 20.
- Luise and Allston Boyer Young Investigator Award for Basic Research (2019)
- NIH Director’s Pioneer Award (2016)
- Pershing Square Sohn Prize for Young Investigators in Cancer Research (2015)
- Damon Runyon-Rachleff Innovation Award, Damon Runyon Cancer Research Foundation (2012)