Andrew Intlekofer is an Assistant Member in the Human Oncology and Pathogenesis Program and an Attending Physician on the Lymphoma Service in the Department of Medicine. Dr. Intlekofer’s research investigates how deregulated metabolic pathways contribute to cancer development and how metabolic enzymes can be targeted for cancer treatment.
Andrew M. Intlekofer, MD, PhD
Assistant Professor
Research Focus
Physician-scientist Andrew Intlekofer investigates why cancer cells depend on specific pathways of nutrient metabolism.Education
MD, PhD, University of Pennsylvania School of Medicine, PA.Lab Members
Giscard Barbier
Laboratory Administrator
Fabian Correa
Senior Research Technician
Naofumi Takemoto
Senior Research Assistant
Bo Wang
Senior Research Technician
Publications
- Intlekofer AM, Wang B, Liu H, Shah H, Carmona-Fontaine C, Rustenburg AS, Salah S, Gunner MR, Chodera JD, Cross JR, Thompson CB. L-2-hydroxyglutarate production arises from non-canonical enzyme function at acidic pH. Nature Chemical Biology. 2017 May;13(5):494-500. doi: 10.1038/nchembio.2307.
- Intlekofer AM, Dematteo RG, Venneti S, Finley LWS, Lu C, Judkins AR, Rustenburg AS, Grinaway, PB, Chodera JD, Cross JR, Thompson CB. Hypoxia Induces Production of L-2-Hydroxyglutarate. Cell Metabolism. 2015 Aug 4; 22(2):304-11.
Selected Achievements
- Burroughs Wellcome Fund Career Award for Medical Scientists (2016)
- NCI K08 Mentored Clinical Scientist Research Career Development Award (2016)
- Steven Greenberg Lymphoma Research Award (MSKCC) (2016)
- Leukemia & Lymphoma Society Special Fellow Award (2015)
- Conquer Cancer Foundation of ASCO Young Investigator Award (2014)
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