Human Oncology & Pathogenesis Program
The Adrienne Boire Lab
Research

Assistant Professor
My laboratory focuses on metastasis to the central nervous system (CNS), both leptomeningeal and parenchymal metastases. We employ multiple complementary approaches to identify and target cancer cell adaptations to the challenging microenvironmental constraints posed by the CNS.
Inside My Lab: Adrienne Boire

Featured News
Publications
Chi Y, Remsik J, Kiseliovas V, Derderian C, Sener U, Alghader M, Saadeh F, Nikishina K, Bale T, Iacobuzio-Donahue C, Thomas T, Pe’er D, Mazutis L and A Boire 2020 Cancer cells deploy lipocalin-2 to collect limiting iron in leptomeningeal metastasis. Science 369(6501):276-282.
Yang TJ, Wijetunga NA, Yamada J, Wolden S, Mehallow M, Goldman DA, Zhang Z, Young RJ, Kris MG, Yu HA, Seidman AD, Gavrilovic IT, Lin A, Santomasso B, Grommes C, Piotrowski AF, Schaff L, Stone JB, DeAngelis LM, Boire A, Pentsova E. 2020 Clinical Trial of Proton Craniospinal Irradiation for Leptomeningeal Metastases Neuro Oncol Jun 27
Malani R, Fleisher M, Kumthekar P, Lin X, Omuro A, Groves MD, Lin NU, Melisko M, Lassman AB, Jeyapalan S, Seidman A, Skakodub A, Boire A, DeAngelis LM, Rosenblum M, Raizer J and E Pentsova 2020 Cerebrospinal Fluid Circulating Tumor Cells as a Quantifiable Measurement of Leptomeningeal Metastases in Patients with HER2 Positive Cancer. Neuro-Oncology Jun 6.
Nevel K, DiStefano N, Lin X, Skakodub A, Ogilvie SQ, Reiner AS, Pentsova E and A Boire 2019 A quantitative assessment of disease burden in patients with leptomeningeal metastases from non-small-cell lung cancer. Neuro-Oncol. 22(5):675-683
Offin M, Feldman D, Ni A, Myers ML, Lai WV, Pentsova E, Boire A, Daras M, Jordan EJ, Solit DB, Arcila ME, Jones DR, Isbell JM, Beal K, Young RJ, Rudin CM, Riely GJ, Drilon A, Tabar V, DeAngelis LM, Yu HA, Kris MG, Li BT 2019 Frequency and Outcomes of Brain Metastases in Patients with HER2-mutant Lung Cancers. Cancer 125(24):4380-4387.
People

Adrienne A. Boire, MD, PhD
Assistant Professor
- Physician-scientist Adrienne Boire studies metastasis to the central nervous system.
- PhD, Tufts University, Boston, MA
- MD, University of Chicago, Chicago, IL
- 646-888-3861
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Members




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Weill Cornell PhD student

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Lab Alumni

Senior Research Technician

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Research Fellow

Clinical Fellow
Lab Affilations
Achievements
- Vienna Medical Academy Award (2017)
- Damon Runyon Clinical Investigator Award (2017)
- Arnold P. Gold Foundation Humanism and Excellence in Teaching Award (2012)
- Pew Biomedical Scholar (2018)
- Pershing Square Sohn Prize (2019)
Open Positions
General Opportunities
Get in Touch
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