Human Oncology & Pathogenesis Program

The Adrienne Boire Lab

Research

Adrienne A. Boire
Adrienne A. Boire, MD, PhD


Associate Professor

My laboratory focuses on metastasis to the central nervous system (CNS), both leptomeningeal and parenchymal metastases. We employ multiple complementary approaches to identify and target cancer cell adaptations to the challenging microenvironmental constraints posed by the CNS.

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The Adrienne Boire Lab Members

Publications Highlights

Wijetunga NA, Goglia AG, Weinhold N, Berger MF, Cislo M, Higginson DS, Chabot K, Osman AM, Schaff L, Pentsova E, Miller AM, Powell SN, Boire A, and JT Yang 2022 Dynamic Mutational Landscape of CSF Circulating Tumor DNA and Predictors of Survival after Proton Craniospinal Irradiation for Leptomeningeal Metastases. Clin Cancer Res Nov 30;CCR-22-2434.

Umemura Y, Khan B, Weill BJ, Buthorn JJ, Skakodub A, Ridder AJ, Nevel KS, Sun Y, and A Boire 2022 Discordance between perceptions and experience of lumbar puncture: A prospective study. Neurol Clin Pract 12(5):344-351.

Yang JT, Wijetunga NA, Pentsova E, Wolden S, Young RJ, Correa D, Zhang Z, Zheng J, Steckler A, Bucwinska W, Bernstein A, Betof Warner A, Yu H, Kris MG, Seidman AD, Wilcox JA, Malani R, Lin A, DeAngelis LM, Lee NY, Powell SN and A Boire 2022 Randomized Phase II Trial of Proton Craniospinal Irradiation Versus Photon Involved-Field Radiotherapy for Patients With Solid Tumor Leptomeningeal Metastasis. J Clin Oncol 40(33):3858-3867.

Remsik J, Chi Y, Tong X, Sener U, Derderian C, ParkA, Saadeh F, Bale T and A Boire2022 Leptomeningeal metastatic cells adopt two phenotypic states. Cancer Rep (Hoboken) 5(4):e1236.

Haddock S, Alban TJ, Turcan Ş, Husic H, Rosiek E, Ma X, Wang Y, Bale T, Desrichard A, Makarov V, Monette S, Wu W, Gardner R, Manova K, Boire A, Chan TA. 2022 Phenotypic and molecular states of IDH1 mutation-induced CD24-positive glioma stem-like cells. Neoplasia 28:100790.

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People

Adrienne A. Boire

Adrienne A. Boire, MD, PhD



Associate Professor

  • Physician-scientist Adrienne Boire studies metastasis to the central nervous system.
  • PhD, Tufts University, Boston, MA
  • MD, University of Chicago, Chicago, IL
646-888-3861
Office Phone
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Physician profile

Members

Ana Rita Lobato Cortesao Nobre
Ana Rita Lobato Cortesao Nobre

Postdoctoral Scholar

Rachel Estrera
Rachel Estrera

Research Technician

Morgan Freret
Morgan Freret

Research Fellow

Branavan Manoranjan
Branavan Manoranjan

Research Fellow

Isaiah Osei-Gyening
Isaiah Osei-Gyening

Research Technician

Sofia Piedrafita-Ortiz
Sofia Piedrafita-Ortiz

MSK Bridge Program Scholar

Jan Remsik, PharmD, PhD
Jan Remsik

Senior Research Scientist

Jenna Snyder
Jenna Snyder

GSK Graduate Student

Clark Thomson

GSK Graduate Student

Xinran Tong
Xinran Tong

Weil Cornell Graduate Student

Rosine Uwayesu

Research Technician

Helen Wang
Helen Wang

Research Technician

Jessica Wilcox
Jessica Wilcox

Assistant Attending Neurologist

Lab Alumni
Majdi Alghader

Senior Research Technician

Giscard Barbier
Giscard Barbier

Administrative Assistant

Kiana Chabot
Kiana Chabot

Research Technician

Yudan Chi

Research Scholar

Camille Derderian

Laboratory Technician

David Gruber
David Gruber

Research Technician

Sara Haddock
Sara Haddock

Graduate Student, Cornell BCMB

Danielle Isakov
Danielle Isakov

Research Technician

Min Jun Li
Min Jun Li

Research Technician

Anestashia Melford
Anestashia Melford

Administrative Assistant

Ahmed Osman
Ahmed Osman

Visiting Investigator

Fadi Saadeh
Fadi Saadeh

Research Fellow

Ugur Sener
Ugur Sener

Clinical Fellow

Lab Affiliations

Achievements

  • 2021 Geoffrey Beene Junior Faculty Chair
  • American Academy of Neurology Neuro Oncology Investigator Award (2020)
  • Pershing Square Sohn Prize (2019)
  • Pew Biomedical Scholar (2018)
  • Damon Runyon Clinical Investigator Award (2017)

Open Positions

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General Opportunities

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Adrienne A. Boire discloses the following relationships and financial interests:

  • Department of Defense/Congressionally Directed Medical Research Programs (CDMRP)
    Professional Services and Activities (Uncompensated)
  • Society for Neuro-Oncology (SNO)
    Professional Services and Activities

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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