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An illustration of two teapots with liquid flowing into various cups
In the Lab
How Stem Cells Decide Their Fate

Research in blood stem cells has revealed new information about how these cells decide what to become when they divide.
An illustration of proteins serving as bar-code-reading drones
In the Lab
“Molecular Origami” Enables Proteins to Serve as Specialized Delivery Vehicles, Study Finds

Scientists at the Sloan Kettering Institute have identified a fundamentally new type of protein-sorting system in cells.
Cancer biologist and pediatric oncologist Alex Kentsis
In the Lab
Analyzing Urine Can Guide the Treatment of Childhood Kidney Tumors

A protein detected in the urine of children with Wilms’ tumor led to the development of a test to improve diagnosis and treatment.
An illustration of sugar pouring onto NRF2
Finding
Sugar Directly Controls a Cancer-Causing Protein, Scientists Find

The discovery suggests a potential new treatment approach for certain cancers.
Computational biologist Barry Taylor
Finding
Whether a BRCA Mutation Leads to Cancer Depends on Context, Study Finds

Sometimes a BRCA mutation is just along for the ride, rather than driving a tumor’s development.
cartoon of man hitting a snooze button
In the Lab
Drug That Hits CAR T Snooze Button Can Quiet a Cytokine Storm

An FDA-approved drug used to treat leukemia can serve as a temporary off switch for CAR T cells, MSK scientists have found.
Fluorescent red and green cells
In the Lab
Scientists Use CRISPR to Learn How Cells Make Decisions

The genome-editing technique uncovered several genes previously not known to influence embryonic development.
DNA winding around histones
In the Lab
Research Clarifies How IDH Mutations Cause Cancer

The MSK team’s goal was to get at the underlying defects in cells that these mutations cause.
Announcement
GSK Students Win Grants to Fund Innovative Cancer Research

Two outstanding graduate students from the Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences (GSK) have been awarded federal funding to pursue promising cancer research.
Colored scanning electron micrograph of a clump of pluripotent stem cells.
In the Lab
Stem Cells Stay “Young” on a Fat-Free Diet

Researchers have discovered a simple way to keep stem cells in a more flexible state for research and potential treatments.