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Decoder
DNA wrapped around histones
What Is Epigenetics?

Physician-scientist Omar Abdel-Wahab explains epigenetics, a growing field based on the study of genetic changes that are not part of the DNA code, and how it relates to cancer.
Finding
Pictured: Gabriela Chiosis
Hsp90: A Very Promising Target for Cancer Therapy

A small molecule discovered at MSK called PU-H71 blocks the growth of cancer cells and enables doctors to image tumors.
Profile
Pictured: David Solit
At Work: Physician-Scientist David Solit

David Solit, Director of the Marie-Josée and Henry R. Kravis Center for Molecular Oncology, discusses how working with cancer patients drives him to develop more-effective, personalized cancer treatments.
Announcement
Pictured: José Baselga, Agnès Viale, Michael Berger & David Solit
Bold Initiative to Transform Cancer Care Established with a $100 Million Gift

With the creation of the Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering sets out to deliver on the promise of personalized medicine by creating better treatment options for all people with cancer.
In the Clinic
New Trial Advances Cell-Based Immune Therapy for Certain Leukemias

A new study evaluating a cell-based immune therapy to treat an aggressive type of leukemia — the largest study of its kind to date — reports that 88 percent of patients responded to the treatment.
In the Clinic
Cell-Based Immune Therapy Shows Promise in Leukemia Patients

Memorial Sloan Kettering researchers have used genetically modified immune cells to eradicate cancer in five patients with acute lymphoblastic leukemia.