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55 News Items found
In the Lab
An illustration of two teapots with liquid flowing into various cups
How Stem Cells Decide Their Fate

Research in blood stem cells has revealed new information about how these cells decide what to become when they divide.
In the Lab
cartoon of man hitting a snooze button
Drug That Hits CAR T Snooze Button Can Quiet a Cytokine Storm

An FDA-approved drug used to treat leukemia can serve as a temporary off switch for CAR T cells, MSK scientists have found.
In the Lab
Fluorescent red and green cells
Scientists Use CRISPR to Learn How Cells Make Decisions

The genome-editing technique uncovered several genes previously not known to influence embryonic development.
In the Lab
DNA winding around histones
Research Clarifies How IDH Mutations Cause Cancer

The MSK team’s goal was to get at the underlying defects in cells that these mutations cause.
In the Lab
Immune cells surrounding a cancer cell
Checkpoint Challenge: When Releasing Immune Cell Brakes Is Not Enough to Stop Cancer

Scientists have learned that cutting a T cell’s brakes can have unexpected consequences.
In the Lab
Two clusters of colored blobs with a diagram in the middle
Computational “Hive Mind” Helps Scientists Solve an Enzyme’s Cryptic Movements

The breakthrough gives an unprecedented look at the varied and shifting poses of a protein in action.
Feature
An illustration of an immune cell killing a cancer cell, and a snake attacking a mouse
How Do Immune Cells Kill Their Prey?

When an immune cell faces a foe, it has more than chemical weapons at its disposal.
In the Lab
Mutlinucleated muscle cells from flies
Scientists Home In On “Equation” for Muscle Cell Size

A new study in flies reveals a previously unknown type of cooperation at work in muscle cells.
Feature
a cartoon of a cancer cell spooning glutamine from a jar
Beyond Sugar: What Cancer Cells Need to Grow

While sugar gets most of the attention as a cancer fuel, other nutrients can be equally important.
In the Lab
In this fluorescent microscopy image of endoderm tissue from a mouse embryo, cell membranes are red, cell nuclei are blue, and extra-embryonic endoderm cells are green (they appear turquoise because blue and green are merged).
Scientists Rewrite the Textbook of Organ Development, One Cell at a Time

A large study that analyzed nearly 120,000 cells in a developing mouse embryo is full of surprises.