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In the Lab
MSK cancer researchers Elizabeth Adams, Charles Sawyers, and Rohit Bose
Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype
Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found.
In the Lab
An illustration of a samurai and a crab.
Ro Versus Musashi: How One Molecule Can Turn Cancer Cells Back to Normal
Researchers identify a compound that appears to eliminate tumor cells in a dish and in mice.
In the Lab
Immune cells surrounding a cancer cell
Checkpoint Challenge: When Releasing Immune Cell Brakes Is Not Enough to Stop Cancer
Scientists have learned that cutting a T cell’s brakes can have unexpected consequences.
In the Lab
Two clusters of colored blobs with a diagram in the middle
Computational “Hive Mind” Helps Scientists Solve an Enzyme’s Cryptic Movements
The breakthrough gives an unprecedented look at the varied and shifting poses of a protein in action.
Feature
An illustration of an immune cell killing a cancer cell, and a snake attacking a mouse
How Do Immune Cells Kill Their Prey?
When an immune cell faces a foe, it has more than chemical weapons at its disposal.
In the Lab
Mutlinucleated muscle cells from flies
Scientists Home In On “Equation” for Muscle Cell Size
A new study in flies reveals a previously unknown type of cooperation at work in muscle cells.
Feature
a cartoon of a cancer cell spooning glutamine from a jar
Beyond Sugar: What Cancer Cells Need to Grow
While sugar gets most of the attention as a cancer fuel, other nutrients can be equally important.
In the Lab
In this fluorescent microscopy image of endoderm tissue from a mouse embryo, cell membranes are red, cell nuclei are blue, and extra-embryonic endoderm cells are green (they appear turquoise because blue and green are merged).
Scientists Rewrite the Textbook of Organ Development, One Cell at a Time
A large study that analyzed nearly 120,000 cells in a developing mouse embryo is full of surprises.
In the News
an illustration of cancer metastasis
AACR 2019 Research Roundup: Nanosensors for Cancer, New Immunotherapy Targets, a Road Map of Metastasis, and CAR T Fratricide
Read our key takeaways from the second half of the American Association for Cancer Research’s 2019 annual meeting.
In the Clinic
Scientific Image
CAR Therapy for Solid Tumors Draws Attention at Annual Cancer Conference
Results from a clinical trial indicate that an experimental CAR therapy for mesothelioma is safe.