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In the Lab
Pictured: Scott Lowe
Researchers Uncover Potential Target for “Undruggable” Form of Liver Cancer

In taking a new approach to finding treatments for hepatocellular carcinoma, MSK scientists have uncovered a potential drug target for this highly aggressive cancer.
In the Lab
Pictured: Experimental Brain Tumor
Genetic “Kill Switch” Could Make Cell Therapies Safer

Researchers have engineered a gene into therapeutic cells that allows them to turn off tumor growth if some of the cells become cancerous.
Pictured: 2014 SURP Students
Another Successful Summer Undergraduate Research Program Comes to a Close

Learn about the experiences and accomplishments of the 2014 Gerstner Sloan Kettering Summer Undergraduate Research Program students during their ten-week course of study.
Snapshot
Pictured: Nematode Worm Embryo
How to Build a Worm, in 3-D High Definition

Stunning movies captured in the lab of computational biologist Zhirong Bao reveal how cells divide, grow, and move around, as in a carefully choreographed dance, during the development of a nematode worm embryo.
In the Lab
Stained pathology slides of a patient’s tumor (right) and of an organoid made from that tumor (left).
Prostate Cancer Organoids Provide New Tool for Evaluating Therapies

Researchers have created tiny structures called organoids from patients’ prostate tumors. These organoids will allow the study of tumors in greater detail and enable correlation of genetic mutations with drug response.
In the Lab
Pictured: Johanna Joyce
Researchers Find Clues to How Breast Cancer Can Infiltrate the Brain

A new study sheds light on what enables breast cancer cells to spread to the brain and presents a potential target for drugs.
Pictured: Jessica Rios-Esteves
Jessica Rios-Esteves Awarded Chairman’s Prize

Gerstner Sloan Kettering student Jessica Rios-Esteves has been awarded the Chairman’s Prize for her first-author paper published in Cell Reports in 2013.
In the Lab
Lab mouse with cultured human pluripotent stem cells
A New Mouse? Genetically Pliable Stem Cells Could Advance Research on Many Diseases

Memorial Sloan Kettering researchers have developed a powerful new way to study human disease using stem cells whose genomes can be manipulated at will.
In the Lab
An origami crane illustrates the importance of RNA folding for regulating gene translation. The bolded sequences on the crane’s wings indicate the portion that is critical for the manufacture of many cancer-causing proteins.
Compound from Tropical Plant Targets Key Cancer-Causing Genes

Memorial Sloan Kettering researchers have found a naturally occurring compound that can destroy cancer cells in mice by targeting <em>MYC</em>, a cancer-causing gene that has remained elusive until now.
Finding
Pictured: Gabriela Chiosis
Hsp90: A Very Promising Target for Cancer Therapy

A small molecule discovered at MSK called PU-H71 blocks the growth of cancer cells and enables doctors to image tumors.