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195 News Items found
In the Lab
Immune cells surrounding a cancer cell
Checkpoint Challenge: When Releasing Immune Cell Brakes Is Not Enough to Stop Cancer

Scientists have learned that cutting a T cell’s brakes can have unexpected consequences.
In the Lab
Two clusters of colored blobs with a diagram in the middle
Computational “Hive Mind” Helps Scientists Solve an Enzyme’s Cryptic Movements

The breakthrough gives an unprecedented look at the varied and shifting poses of a protein in action.
Feature
An illustration of an immune cell killing a cancer cell, and a snake attacking a mouse
How Do Immune Cells Kill Their Prey?

When an immune cell faces a foe, it has more than chemical weapons at its disposal.
In the Lab
Mutlinucleated muscle cells from flies
Scientists Home In On “Equation” for Muscle Cell Size

A new study in flies reveals a previously unknown type of cooperation at work in muscle cells.
Finding
Drawing of one human figure set apart from a group of others.
One Patient’s Exceptional Response Leads to a Surprising Discovery about Immunotherapy

MSK researchers learn that some cancers may respond to checkpoint inhibitor drugs because of changes called gene fusions.
Feature
a cartoon of a cancer cell spooning glutamine from a jar
Beyond Sugar: What Cancer Cells Need to Grow

While sugar gets most of the attention as a cancer fuel, other nutrients can be equally important.
Science Byte
Ribbon diagram of an anthrax protein.
Scientists Discover Keys to Immune Response against Anthrax

Researchers clarify how the immune system activates an inflammatory defense against pathogens.
In the Lab
In this fluorescent microscopy image of endoderm tissue from a mouse embryo, cell membranes are red, cell nuclei are blue, and extra-embryonic endoderm cells are green (they appear turquoise because blue and green are merged).
Scientists Rewrite the Textbook of Organ Development, One Cell at a Time

A large study that analyzed nearly 120,000 cells in a developing mouse embryo is full of surprises.
Feature
Model of TGF-beta molecule
An Old Protein Gets a New Look: Researchers Target TGF-ß to Make Immunotherapy More Effective

Drugs that block the action of TGF-ß may make checkpoint inhibitors more effective.
In the News
an illustration of cancer metastasis
AACR 2019 Research Roundup: Nanosensors for Cancer, New Immunotherapy Targets, a Road Map of Metastasis, and CAR T Fratricide

Read our key takeaways from the second half of the American Association for Cancer Research’s 2019 annual meeting.