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The Andrew Intlekofer Lab
The David Solit Lab
The Minkui Luo Lab
The Joseph Sun Lab
The Ming Li Lab
The Ross Levine Lab
The Jennifer Zallen Lab
The Steven Larson Lab
Donor T cells are reactive against and effective in adoptive immunotherapy of Epstein-Barr virus (EBV) lymphomas, which develop in some leukemia patients after marrow transplantation. Such T cells have been genetically modified by incorporation of a replication-incompetent vector (NIT) for an inactive mutant nerve growth factor receptor (LNGFR) as an immunoselectable surface marker and a herpes simplex virus thymidine kinase gene (HSV-TK), rendering the cells sensitive to ganciclovir.
The Santosha Vardhana Lab
The Michael Glickman Lab