Clinical Trials

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Patients treated at MSK have access to a number of CAR T-based clinical trials. To identify available trials, search the box below.

Adult

Leukemia

19-085 (Dr. Geyer) A Phase I/II Study of CAR T-Cell Therapy to Treat Persistent or Recurrent Chronic Lymphocytic Leukemia

20-135 (Dr. Sauter) A Phase I/IIA Study of PBCAR0191 Immunotherapy in People with Recurrent or Persistent Non-Hodgkin Lymphoma and B-Cell Acute Lymphoblastic Leukemia

Lymphoma

15-295 (Dr. Palomba) A Phase I Study of Immunotherapy with Genetically Modified T Cells to Treat Recurrent or Persistent B-Cell Non-Hodgkin Lymphoma

20-010 (Dr. Younes) A Phase I Study of AUTO3 CAR T-Cell Therapy with Pembrolizumab Immunotherapy in People with Recurrent or Persistent Diffuse Large B-Cell Lymphoma

20-135 (Dr. Sauter) A Phase I/IIA Study of PBCAR0191 Immunotherapy in People with Recurrent or Persistent Non-Hodgkin Lymphoma and B-Cell Acute Lymphoblastic Leukemia

20-167 (Dr. Park) A Phase I Study of CD19-Targeted CAR T-Cell Therapy to Treat Patients with Recurrent or Persistent B-Cell Leukemia or Lymphoma

Lung Cancer/Breast Cancer/Mesothelioma

15-007 (Dr. Adusumilli) A Phase I Study of Immunotherapy with Genetically Engineered T Cells (CAR T Cells) to Treat Mesothelioma and Malignant Pleural Disease from Lung and Breast Cancers

Breast Cancer
Ovarian Cancer

15-014 (Dr. O’Cearbhaill) A Phase I Study of Immunotherapy with Genetically Modified T Cells plus Cyclophosphamide to Treat Recurrent High-Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Multiple Myeloma

19-392 (Dr. Mailankody) A Phase I Study of ALLO-647 with ALLO-715 CAR T-Cell Therapy in People with Recurrent or Persistent Multiple Myeloma

Pediatric

Leukemia

11-038 (Dr. Curran) A Phase I Study of Modified T Cells Targeted to CD19-Positive Acute Lymphoblastic Leukemia Relapsing After Allogeneic Stem Cell Transplantation