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In the Lab
MSK immunologist Ming Li.
MSK-led Studies Support the Concept of “Cancer Environment Immunotherapy”
Targeting the cancer environment, rather than the cancer itself, could be a new avenue for immunotherapy.
Q&A
MSK developmental biologist Lorenz Studer
Taking Aim at Parkinson’s Disease: A Conversation with Developmental Biologist Lorenz Studer
In an interview in September 2020, Dr. Studer spoke about what he hopes he and his fellow investigators can accomplish with this generous support.
Regulatory proteins (gold balls) bind to enhancer regions (light blue) and promoter regions (pink) of DNA to form clusters that enable transcription (purple).
Going the Distance: How DNA Enhancers Communicate with Their Target Genes
Scientists at the Sloan Kettering Institute are learning how far-flung regions of genes connect to start the process of making proteins.
Finding
Section of a lung cancer tumor in mice
A Never-Before-Seen Cell State May Explain Cancer’s Ability to Resist Drugs
Identified in mice, this unusual cell state emerges early during tumor evolution and gives tumors enormous malleability.
MSK physician-scientists Michael Glickman and Gil Redelman-Sidi
The ABCs of BCG: Oldest Approved Immunotherapy Gets New Explanation
BCG has been used to treat bladder cancer for more than 30 years. Scientists are still learning how it works.
In the Lab
An illustration of sugar being sprinkled on a cancer cell.
Just Add Sugar: How a Protein’s Small Change Leads to Big Trouble for Cells
A study from investigators in the Sloan Kettering Institute uncovers the details of how a key protein called GRP94 becomes disrupted, leading to cancer and other diseases.
In the Lab
Confocal microscopy image of a female fruit fly brain.
How Fruit Flies Know When They've Mated
Research from investigators at the Sloan Kettering Institute shows how a brain circuit controls mating behavior in fruit flies.
In the Lab
CT scan showing lymphoma in the abdomen between the liver and the gallbladder.
A Metabolic Enzyme Drives Lymphoma and Is a Potential Drug Target
New research from Sloan Kettering Institute investigators pinpoints altered cell metabolism as a cause of B cell lymphoma.
In the Lab
Fluorescent image of CAR T cells in mouse liver fibrosis
A New Target for CAR T Cells: Senescence-Related Diseases
From atherosclerosis and diabetes to liver fibrosis and osteoarthritis, senescent cells are at the root of many debilitating diseases. Scientists increasingly have them in the crosshairs.
Event
MSK leadership on the stage in the Zuckerman Research Center auditorium.
MSK’s Virtual Convocation and Commencement Honors Graduates and Award Winners
Memorial Sloan Kettering’s 41st annual ceremony recognized graduates and award winners with an online event.