Molecular Biology Program

The Xiaohui Qu Lab

Research

Xiaohui Qu, PhD

Assistant Professor

My lab conducts high-resolution, single-molecule studies of the molecular mechanisms of ribosome functions and gene expression control.

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Publications

Wang H, Sun L, Gaba A, Qu X. An in vitro single-molecule assay for eukaryotic cap-dependent translation initiation kinetics. Nucleic Acids Res. 2019 Nov 13. pii: gkz1066. doi: 10.1093/nar/gkz1066. [Epub ahead of print]

X Qu. Single-Molecule Optical Tweezers Studies of Translation. Biophysics of RNA-Protein Interactions, 143-164

Zhovmer A and Qu X. Proximal disruptor aided ligation (ProDAL) of kilobase-long RNAs. RNA Biol. 2016 Jul 2;13(7):613-21.

Qu X, Lancaster L, Noller HF, Bustamante C, and Tinoco I, Jr. Ribosomal protein S1 unwinds double-stranded RNA in multiple steps. Proc Natl Acad Sci USA. 2012 September 4;109(36):14458-14463.

Qu X, Wen J-D, Lancaster L, Noller HF, Bustamante C, and Tinoco I, Jr. The ribosome uses two active mechanisms to unwind messenger RNA during translation. Nature. 2011 Jul 6;475(7354):118-21. doi: 10.1038/nature10126.

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People

Xiaohui Qu, PhD

Assistant Professor

Molecular biologist Xiaohui Qu conducts high-resolution, single-molecule studies of the molecular mechanisms of ribosome functions and gene expression control.
PhD, University of Chicago

qux@mskcc.org: Email Address
212-639-2020: Office Phone

Members

Anthony Gaba, PhD — Anthony Gaba
Senior Research Scientist

Hongyun Wang, PhD — Hongyun Wang
Research Associate

Lab Alumni

Alexander Zhovmer, PhD — Alexander Zhovmer
Research Fellow

Lab Affilations

Open Positions

Career Opportunities

Postdoctoral positions are available.

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Postdoctoral Position

Postdoctoral opening in single-molecule studies of translational control of gene expression Memorial Sloan Kettering Cancer Center – New York, NY We are a single-molecule lab that develops and applies high-resolution single-molecule optical techniques to study the molecular mechanisms of protein synthesis and translational control of gene expression.

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Get in Touch

qux@mskcc.org

Lab Head Email
212-639-2020

Office Phone
212-639-8693

Lab Phone

Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Xiaohui Qu discloses the following relationships and financial interests:

No disclosures meeting criteria for time period

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.

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