The focus of my laboratory is to understand the genomic basis of tumor development and treatment response. We use both large-scale genomic analyses and functional dissection to determine what drives oncogenesis. From this information, we seek to develop improved diagnostic and therapeutic modalities for human cancers.
Timothy A. Chan, MD, PhD
Professor
Research Focus
Physician-scientist Timothy Chan focuses on the characterization of genetic determinants underlying response and resistance to cancer therapeutics.Education
MD, PhD, The Johns Hopkins University School of Medicine- For patient-related issues 212-639-8904
- For non-clinical issues only 646-888-2765
- Lab Phone: 646-888-2783
Lab Members
Kyle Blum
Research Fellow
Timothy A. Chan
Principal Investigator
Diego Chowell
Research Fellow
Renzo DiNatale
Research Fellow
Yiyu Dong
Senior Research Scientist
Ian Ganly
Assistant Attending Surgeon
Yongxing Gong
Research Fellow
Sara Haddock
Weill Cornell PhD Student
Jonathan Havel
Research Scholar
Doug Hoen
Bioinformatics Engineer III
Sviatoslav Kendall
Bioinformatics Technician
Chirag Krishna
Computational Biology PhD Student
Xiaoxioa Ma
Research Fellow
Vladimir Makarov
Bioinformatics Engineer III; Head of Software Engineering, Immunogenetics and Precision Oncology Platform
Ryan Marren
Bioinformatics Engineer I
Luc G. T. Morris
Associate Attending Surgeon
Zaineb Nadeem
Research Technician Sr.
Tanaya Purohit
Research Technician
Nadeem Riaz
Assistant Attending
Erich Sabio
Research Fellow
Robbie Samstein
Resident Physician Research Fellow
Alejandro Sanchez
Urologic Oncology Fellow
Kristy Schmicking
Program Assistant
Rachna Shah
Research Technician
Raghvendra Srivastava
Senior Research Scientist
Lynda Vuong
Research Fellow
Shiyang Wang
Project Portfolio Manager
Yuxiang Wang
Research Fellow
Aaron Wild
Resident Physician Research Fellow
Zhang Xiao
Graduate Research Assistant
Wei (Vera) Yang
Research Fellow
Publications
- Veeriah S, Brennan C, Meng S, Singh B, Fagin JA, Solit DB, Paty PB, Rohle D, Vivanco I, Chmielecki J, Pao W, Ladanyi M, Gerald WL, Liau L, Cloughesy TC, Mischel PS, Sander C, Taylor B, Schultz N, Major J, Heguy A, Fang F, Mellinghoff IK, Chan TA. The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers. Proceedings of the National Academy of Science USA 2009.
- Fang Fang, Sevin Turcan, Andreas Rimner, Andrew Kaufman, Dilip Giri, Luc G. T. Morris, Ronglai Shen, Venkatraman Seshan, Qianxing Mo, Adriana Heguy, Stephen B. Baylin, Nita Ahuja, Agnes Viale, Joan Massague, Larry Norton, Linda T. Vahdat, Mary Ellen Moynahan, and Timothy A. Chan (2011) Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis. Science Translational Medicine 3, 1-12.
Selected Achievements
- Era of Hope Scholar, Department of Defense (2012)
- Frederick R. Adler Chair for Junior Faculty, Memorial Sloan Kettering Cancer Center (2012)
- Member, American Society of Clinical Investigation (2012)
- Distinguished Scientist Award, Sontag Foundation (2010)
- Han-Mo Koo Memorial Lectureship Award, Van Andel Institute (2010)
