Molecular Biology Program

The Thomas Kelly Lab

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Research

Pictured: Thomas Kelly
Thomas J. Kelly, MD, PhD
Benno S. Schmidt Chair of Cancer Research; Member, Memorial Sloan Kettering Cancer Center; Professor, Weill Graduate School of Biomedical Sciences, Cornell University

Professor

My long-term interest is to understand how the cellular genome is duplicated during the cell cycle. In the course of growth and division, eukaryotic cells duplicate their genomes with remarkable fidelity. The precision of this process depends in large measure upon stringent regulatory mechanisms that couple DNA replication to cell cycle progression. Initiation must be triggered at the appropriate time in the cell cycle at many hundreds or thousands of separate sites (origins of DNA replication) in the parental chromosomes. However, initiation must be prevented at these same sites in the newly synthesized daughter chromosomes. These controls ensure that each DNA segment in the genome is duplicated in a timely fashion exactly once each cell cycle.

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People

Pictured: Thomas Kelly

Thomas J. Kelly, MD, PhD

Benno S. Schmidt Chair of Cancer Research; Member, Memorial Sloan Kettering Cancer Center; Professor, Weill Graduate School of Biomedical Sciences, Cornell University

Professor

  • Molecular biologist Thomas Kelly studies regulatory mechanisms that control DNA replication during the cell cycle of eukaryotic cells.
  • MD, PhD, Johns Hopkins University School of Medicine
tkelly@mskcc.org
Email Address
212-639-8614
Office Phone

Members

Lab Alumni
Thomas J. Kelly, MD, PhD
Thomas J. Kelly

Lab Head

John Callegari

Senior Research Scientist

Ronghua Zhang

Research Technician

Lucia Regales

Research Associate

Ryan George

Graduate Student

Wenyan Lu

Graduate Student

Pamela Simancek

Senior Research Technician

Min Wu

Research Fellow

Lab Affilations

Achievements

  • Former Director, Sloan Kettering Institute 2002-2013
  • Doctor of Science, honoris causa, Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences 2014
  • Louisa Gross Horwitz Prize 2010
  • Johns Hopkins Society of Scholars 2010
  • Alfred P. Sloan Jr Prize, General Motors Cancer Research Foundation
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  • Member, Institute of Medicine 2000
  • Member, American Philosophical Society 1998
  • Member, National Academy of Sciences 1992
  • Fellow, American Academy of Arts and Sciences 1989
  • Fellow, American Association for the Advancement of Science 1986

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Thomas J. Kelly discloses the following relationships and financial interests:

  • Lin BioScience, Inc.
    Intellectual Property Rights
  • Peloton Therapeutics
    Ownership / Equity Interests

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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