Koyi Choi

Former Graduate Student
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Koyi Choi

Education

BS in Molecular and Cellular Biology, Johns Hopkins University; PhD Student, Weill Graduate School of Medical Sciences of Cornell University

Current position
Patent Agent, Wilson Sonsini Goodrich & Rosati, Palo Alto, CA, USA

Publications

Yu Y, Li S, Ser Z, Sanyal T, Choi K, Wan B, Kuang H, Sali A, Kentsis A, Patel DJ, Zhao X (2021). Integrative analysis reveals unique structural and functional features of the Smc5/6 complex. Proc Natl Acad Sci U S A. 118(19):e2026844118..

Bonner JN, Choi K, Xue X, Torres NP, Szakal B, Wei L, Wan B, Arter M, Matos J, Sung P, Brown GW, Branzei D, Zhao X. Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates. Cell Rep. 2016 Jul 12;16(2):368-378. doi: 10.1016/j.celrep.2016.06.015. Epub 2016 Jun 30. PubMed [PMID: 27373152]; PubMed Central PMCID: PMC5051638.

Dummer AM, Su Z, Cherney R, Choi K, Denu J, Zhao X, Fox CA. Binding of the Fkh1 Forkhead Associated Domain to a Phosphopeptide within the Mph1 DNA Helicase Regulates Mating-Type Switching in Budding Yeast. PLoS Genet. 2016 Jun;12(6):e1006094. doi: 10.1371/journal.pgen.1006094. eCollection 2016 Jun. PubMed [PMID: 27257873]; PubMed Central PMCID: PMC4892509.

Xue X, Papusha A, Choi K, Bonner JN, Kumar S, Niu H, Kaur H, Zheng XF, Donnianni RA, Lu L, Lichten M, Zhao X, Ira G, Sung P. Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by Mte1. Genes Dev. 2016 Mar 15;30(6):687-99. doi: 10.1101/gad.276139.115. Epub 2016 Mar 10. PubMed [PMID: 26966246]; PubMed Central PMCID: PMC4803054.

Xue X, Choi K, Bonner JN, Szakal B, Chen YH, Papusha A, Saro D, Niu H, Ira G, Branzei D, Sung P, Zhao X. Selective modulation of the functions of a conserved DNA motor by a histone fold complex. Genes Dev. 2015 May 15;29(10):1000-5. doi: 10.1101/gad.259143.115. Epub 2015 May 8. PubMed [PMID: 25956905]; PubMed Central PMCID: PMC4441048.

Choi K, Batke S, Szakal B, Lowther J, Hao F, Sarangi P, Branzei D, Ulrich HD, Zhao X.Concerted and differential actions of two enzymatic domains underlie Rad5 contributions to DNA damage tolerance. Nucleic Acids Res. 2015 Mar 11;43(5):2666-77. doi: 10.1093/nar/gkv004. Epub 2015 Feb 17. PubMed [PMID: 25690888]; PubMed Central PMCID: PMC4357696.

Xue X, Choi K, Bonner J, Chiba T, Kwon Y, Xu Y, Sanchez H, Wyman C, Niu H, Zhao X, Sung P. Restriction of replication fork regression activities by a conserved SMC complex. Mol Cell. 2014 Nov 6;56(3):436-45. doi: 10.1016/j.molcel.2014.09.013. Epub 2014 Oct 16. PubMed [PMID: 25439736]; PubMed Central PMCID: PMC4268010.

Choi K, Szakal B, Chen YH, Branzei D, Zhao X. The Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiae. Mol Biol Cell. 2010 Jul 1;21(13):2306-14. doi: 10.1091/mbc.e10-01-0050. Epub 2010 May 5. PubMed [PMID: 20444977]; PubMed Central PMCID: PMC2893993.

Chen YH, Choi K, Szakal B, Arenz J, Duan X, Ye H, Branzei D, Zhao X. Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repair. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21252-7. doi: 10.1073/pnas.0908258106. Epub 2009 Dec 7. PubMed [PMID: 19995966]; PubMed Central PMCID: PMC2795505.