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28 News Items found
In the Lab
Fluorescent image of mouse prostate gland
New Discovery Explains How the Prostate Gland Regenerates Itself

Androgen-deprivation therapy, a mainstay of prostate cancer treatment, may give prostate cells new growth abilities, scientists at Memorial Sloan Kettering have found.
In the Lab
Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh
When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.
Science Byte
Cancer biologist and pediatric oncologist Alex Kentsis
Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers

A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.
In the Lab
Cancer biologist and pediatric oncologist Alex Kentsis
Jumping Genes and the Dark Genome: MSK Researchers Gain New Insight into Childhood Cancers

Researchers have discovered a genetic mechanism that may trigger most childhood cancers.
In the Lab
Organoid cell structures fluorescing in blue, green, and purple.
Manipulating a Single Gene Turns Colorectal Cancer Cells Back to Normal

For the first time, scientists have shown that the gene APC, which is mutated in the vast majority of colorectal cancers, might be a promising target for future therapies.
In the Lab
Portrait of a live zebrafish with dark patterning around and above the eyes
Uncharted Waters: The Making of a New Cancer Drug

A team of scientists is combining sophisticated chemistry and experiments in zebrafish to develop a new cancer drug that shows early potential against melanoma and metastatic breast cancer.
In the Lab
MSK investigators Joan Massagué and Anna Obenauf
Outsmarting Cancer’s Survival Skills

A new study led by MSK investigators reveals how some cancer cells become resistant to targeted treatment and suggests what might be done to stop that from happening.
In the Lab
Cancer biologist Andrea Ventura
Disorderly DNA: Researchers Simulate a Common Cause of Lung Cancer

MSK scientists have created a mouse model that replicates a subtype of non-small cell lung cancer caused by a chromosomal rearrangement.
In the Lab
Pictured: Scott Lowe
Researchers Uncover Potential Target for “Undruggable” Form of Liver Cancer

In taking a new approach to finding treatments for hepatocellular carcinoma, MSK scientists have uncovered a potential drug target for this highly aggressive cancer.
In the Lab
Stained pathology slides of a patient’s tumor (right) and of an organoid made from that tumor (left).
Prostate Cancer Organoids Provide New Tool for Evaluating Therapies

Researchers have created tiny structures called organoids from patients’ prostate tumors. These organoids will allow the study of tumors in greater detail and enable correlation of genetic mutations with drug response.