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21 News Items found
In the Lab
An illustration of lung develop alongside tumor evolution
Shape-Shifting Stem Cells Are Key to Cancer Metastasis and Immune Evasion

By assuming primitive regenerative identities, cancer cells gain the adaptability they need to establish tumors in new parts of the body.
In the Lab
Graphical representation of cells leaking into bloodstream
What Does Cancer Metastasis Have to Do with Wound Healing? More than You Might Think

Scientists are learning that — in a literal sense — metastasis is wound healing gone wrong.
In the Lab
Epithelial cells
Mind the Gap: Scientists Learn How Cells Make and Repair Tight Connections

New findings from researchers at the Sloan Kettering Institute provide insight into a fundamental biological process called the epithelial-mesenchymal transition.
In the Lab
This image shows cancer cells (white) and pericytes (green) clinging to capillaries (red). The blue dots are nuclei.
Scientists Identify Growth Signal for Metastatic Cancer "Seeds"

Targeting this signal with drugs might be one way to stop cancers from spreading.
In the Lab
Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh
When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.
In the Lab
a sneaky man on a sneaky mission
Stealth Mode: How Metastatic Cancer Cells Evade Detection by the Immune System

Cancer cells have a sneaky ability to hide out in the body for years at a time. MSK scientists are looking for ways to flush them out.
In the Lab
Pictured: Casper zebrafish
Studying Cancer Mysteries Just Beneath the Scales

Hail to the zebrafish. MSK scientists are using a small fish to answer some big questions about cancer.
In the Lab
MSK investigators Joan Massagué and Anna Obenauf
Outsmarting Cancer’s Survival Skills

A new study led by MSK investigators reveals how some cancer cells become resistant to targeted treatment and suggests what might be done to stop that from happening.
Finding
MSK investigators Michael Berger and David Solit.
Study Reveals How Some Breast Cancers Become Resistant to Targeted Drugs

A study of one patient’s disease has clarified why tumors stop responding to a class of experimental drugs called PI3K inhibitors.
In the Lab
Pictured: Scott Lowe
Researchers Uncover Potential Target for “Undruggable” Form of Liver Cancer

In taking a new approach to finding treatments for hepatocellular carcinoma, MSK scientists have uncovered a potential drug target for this highly aggressive cancer.