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16 News Items found
In the Lab
An illustration of a samurai riding a horse along a strand of RNA. The samurai’s sword is changing the letter A to the letter I.
Novel Tool Enables Study of Rare Acute Myeloid Leukemia Stem Cells
MSK investigators have used a lab tool originally developed to study fly nerve cells to uncover new findings about acute myeloid leukemia.
Feature
Cancer biologist Scott Lowe at a white board
Researchers Find that Vitamin B6 Contributes to Survival of Acute Myeloid Leukemia Cells
This research marks the first time researchers have found a connection between vitamin B6 and cancer.
In the Lab
Microscopy image of vancomycin-resistant Enterococcus
Researchers Identify a Bacterial Species That Could Protect against Hospital-Acquired Infections
MSK researchers are reporting that a bacterial species called Blautia producta appears to release a substance that kills harmful bacteria.
In the Lab
An illustration of a samurai and a crab.
Ro Versus Musashi: How One Molecule Can Turn Cancer Cells Back to Normal
Researchers identify a compound that appears to eliminate tumor cells in a dish and in mice.
In the Lab
An illustration shows Helios, the ancient Greek sun god, unwinding DNA
Something New Under the Sun: Study in Leukemia Finds Role for Helios Protein
MSK researchers have found that a protein that contributes to one type of leukemia when it’s missing can lead to the formation of a different leukemia type when it’s present.
Announcement
Acute myeloid leukemia cells under a microscope
FDA Approves Enasidenib (Idhifa), a First-of-Its-Kind Drug, for Advanced Blood Cancer
A new treatment option for people with acute myeloid leukemia is available, and it works in an unconventional way.
In the Lab
Histology images of stem cells and AML cells
Step by Step: Stem Cell Approach Provides New Models for Studying How Acute Myeloid Leukemia Progresses
A new laboratory tool will allow researchers to study the progression from normal cells to myelodysplastic syndromes to an aggressive type of leukemia.
In the Clinic
Pictured: Charles Sawyers
The Evolution of a Lifesaving Drug: A Scientist Reflects
Physician-scientist Charles Sawyers played a pivotal role in the development of Gleevec, one of the first successful targeted drugs for cancer.
Decoder
DNA wrapped around histones
What Is Epigenetics?
Physician-scientist Omar Abdel-Wahab explains epigenetics, a growing field based on the study of genetic changes that are not part of the DNA code, and how it relates to cancer.
In the Lab
An origami crane illustrates the importance of RNA folding for regulating gene translation. The bolded sequences on the crane’s wings indicate the portion that is critical for the manufacture of many cancer-causing proteins.
Compound from Tropical Plant Targets Key Cancer-Causing Genes
Memorial Sloan Kettering researchers have found a naturally occurring compound that can destroy cancer cells in mice by targeting <em>MYC</em>, a cancer-causing gene that has remained elusive until now.
In the Clinic
New Trial Advances Cell-Based Immune Therapy for Certain Leukemias
A new study evaluating a cell-based immune therapy to treat an aggressive type of leukemia — the largest study of its kind to date — reports that 88 percent of patients responded to the treatment.
In the News
New Biotech Startup Will Pit the Immune System Against Cancer
Memorial Sloan Kettering’s partnership in a pioneering effort to speed the development of cancer immunotherapies drew national headlines.
In the Clinic
Cell-Based Immune Therapy Shows Promise in Leukemia Patients
Memorial Sloan Kettering researchers have used genetically modified immune cells to eradicate cancer in five patients with acute lymphoblastic leukemia.
In the Lab
Pictured: ESK1 Monoclonal Antibody
New Molecule Targets Proteins Inside Cancer Cells
Scientists from Memorial Sloan Kettering have collaborated on the discovery of a unique monoclonal antibody, called ESK1, that appears to be effective at targeting and destroying several types of cancer cells.
In the Lab
Pictured: Ross Levine
Researchers Discover Why Some Leukemia Drugs Are Not Sufficiently Effective
Memorial Sloan Kettering researchers have found why certain drugs are not sufficiently effective in treating leukemias called myeloproliferative neoplasms.
Profile
Pictured: Hans-Guido Wendel
Genetic Causes of Blood Cancers Explored
German-born cancer biologist Hans-Guido Wendel is taking advantage of transformative advances in genomics technology to understand key genetic abnormalities in leukemia and lymphoma.