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11 News Items found
In the Lab
Memorial Sloan Kettering computational biologist Ed Reznik.
Hiding in Plain Sight: Mitochondrial DNA May Hold Overlooked Cancer Clues
DNA in the mitochondria of cancer cells may yield insights that lead to more accurate prognoses and new treatment strategies.
In the Lab
CT scan showing lymphoma in the abdomen between the liver and the gallbladder.
A Metabolic Enzyme Drives Lymphoma and Is a Potential Drug Target
New research from Sloan Kettering Institute investigators pinpoints altered cell metabolism as a cause of B cell lymphoma.
In Brief
A fluorescent image of cells undergoing differentiation in a mouse model.
Cancer Stem Cells’ Reliance on a Key Amino Acid Could Be an Exploitable Weakness
The discovery links metabolism to the way cancer stem cells form tumors.
Feature
Cancer biologist Scott Lowe at a white board
Researchers Find that Vitamin B6 Contributes to Survival of Acute Myeloid Leukemia Cells
This research marks the first time researchers have found a connection between vitamin B6 and cancer.
In the Lab
illustration of the p53 protein binding to a DNA helix
New Findings Clarify How the “Guardian of the Genome” Works
Surprise! It has to do with metabolism.
Feature
a cartoon of a cancer cell spooning glutamine from a jar
Beyond Sugar: What Cancer Cells Need to Grow
While sugar gets most of the attention as a cancer fuel, other nutrients can be equally important.
In the Lab
Enhanced MRI of a glioblastoma
Starving Cancer Stem Cells Could Be the Trick to Treating Glioblastoma, Study Finds
MSK researchers have identified a compound that kills glioblastoma cells using a mechanism that’s completely different from earlier treatments.
Finding
Large cells filled with yellow-colored fat
Cancer Cells Eat Fat to Grow and Spread
Research conducted in zebrafish shows that melanoma cells have an affinity for fat, and that eating it makes them more aggressive.
In the Lab
abstract red and blue lines suggestive of metabolic pathways
Scientists Create First-of-Its-Kind Metabolic Road Map of Cancer
The online resource will serve as a benchmark for researchers studying metabolism and cancer.
Feature
Pictured: Macrophage & Tumor Cells
Turning to Bacteria for Cancer Clues
Approaches used for research into the social lives of bacteria can also be used to explore how tumors behave and evolve.
In the Lab
Pictured: Timothy Chan
Studies Show How Certain Gene Mutations May Promote Cancer
Two Memorial Sloan Kettering studies provide new clues about genetic mutations that affect cell behavior and play a role in several types of cancer.