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65 News Items found
In the Lab
Memorial Sloan Kettering computational biologist Ed Reznik.
Hiding in Plain Sight: Mitochondrial DNA May Hold Overlooked Cancer Clues
DNA in the mitochondria of cancer cells may yield insights that lead to more accurate prognoses and new treatment strategies.
Finding
Section of a lung cancer tumor in mice
A Never-Before-Seen Cell State May Explain Cancer’s Ability to Resist Drugs
Identified in mice, this unusual cell state emerges early during tumor evolution and gives tumors enormous malleability.
In the Lab
CT scan showing lymphoma in the abdomen between the liver and the gallbladder.
A Metabolic Enzyme Drives Lymphoma and Is a Potential Drug Target
New research from Sloan Kettering Institute investigators pinpoints altered cell metabolism as a cause of B cell lymphoma.
In the Lab
Graphical representation of cells leaking into bloodstream
What Does Cancer Metastasis Have to Do with Wound Healing? More than You Might Think
Scientists are learning that — in a literal sense — metastasis is wound healing gone wrong.
Finding
Pedram Razavi, Jorge Reis-Filho, and Bob Li
Many Mutations Detected in Liquid Biopsy Tests Do Not Come from Cancer Cells, an MSK Study Finds
The new findings suggest the need for caution when interpreting the results from these tests.
In the Lab
illustration of the p53 protein binding to a DNA helix
New Findings Clarify How the “Guardian of the Genome” Works
Surprise! It has to do with metabolism.
Finding
An illustration of sugar pouring onto NRF2
Sugar Directly Controls a Cancer-Causing Protein, Scientists Find
The discovery suggests a potential new treatment approach for certain cancers.
In the Lab
MSK cancer researchers Elizabeth Adams, Charles Sawyers, and Rohit Bose
Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype
Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found.
In the Lab
An illustration of a samurai and a crab.
Ro Versus Musashi: How One Molecule Can Turn Cancer Cells Back to Normal
Researchers identify a compound that appears to eliminate tumor cells in a dish and in mice.
Feature
a cartoon of a cancer cell spooning glutamine from a jar
Beyond Sugar: What Cancer Cells Need to Grow
While sugar gets most of the attention as a cancer fuel, other nutrients can be equally important.
In the News
AACR 2019 Annual Meeting
AACR 2019 Research Roundup: Pancreatic Cancer Immunotherapy, Prostate Cancer Drug Resistance, Insight into Inherited Cancer Mutations
Read up on the latest developments in several important areas of cancer research emerging from the 2019 American Association for Cancer Research annual meeting.
In the Lab
Enhanced MRI of a glioblastoma
Starving Cancer Stem Cells Could Be the Trick to Treating Glioblastoma, Study Finds
MSK researchers have identified a compound that kills glioblastoma cells using a mechanism that’s completely different from earlier treatments.
Finding
Alex Kentsis in his lab
Research Uncovers the Genetic Causes of Aggressive Leukemia in Children
Researchers have found that the genetic changes that cause pediatric leukemia are different from those that lead to leukemia in adults.
In the Clinic
Image of a mobile phone with a strand of DNA
There’s an App for That: When the Meaning of a BRCA Mutation Isn’t Clear-Cut
A new project called the BRCA Exchange is sharing data about BRCA mutations and what they actually mean for cancer risk.
In the Lab
electron micrograph of a natural killer cell
Drugs That Stall — But Don’t Kill — Cancer Cells Are an Untapped Resource, Study Suggests
A drug combination that halts tumor cell division can stir the immune system into taking action.
In the Clinic
A tube of blood superimposed on a lung and a DNA helix
Liquid Biopsy Is Effective at Guiding Treatment of Lung Cancer, Study Finds
The initial results of an ongoing study show that a liquid biopsy has advantages over a tissue biopsy for people with lung cancer.
In the Lab
Sloan Kettering Institute molecular biologist Christine Mayr
Scientists Find Cancer Drivers Hiding in a New Place
New findings from researchers at the Sloan Kettering Institute suggest that cancer causes may be lurking in the molecule that bridges DNA and protein.
In the Lab
This image shows cancer cells (white) and pericytes (green) clinging to capillaries (red). The blue dots are nuclei.
Scientists Identify Growth Signal for Metastatic Cancer "Seeds"
Targeting this signal with drugs might be one way to stop cancers from spreading.
In the Lab
A microscopic view of genetically engineered mouse tumor and a human FL-HCC tumor
With Help of CRISPR, Scientists Unravel the Cause of a Rare Liver Cancer
A team led by MSK molecular biologist Scott Lowe is making progress against fibrolamellar hepatocellular carcinoma.
Science Byte
Cancer biologist and pediatric oncologist Alex Kentsis
Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers
A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.