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In the Lab
CAR T cells attacking cancer
CRISPR Genome-Editing Tool Takes Cancer Immunotherapy to the Next Level
What do you get when you combine two of the hottest areas of biotechnology? A new paper from MSK researchers explains.
In the Lab
Image of fireball-type explosion on black background.
Researchers Gain Insight into How a Drug Fires Up an Immune Response to Cancer
Scientists have learned that a drug activates a form of highly inflammatory programmed cell death called pyroptosis — a discovery that sheds light on immune function.
Q&A
Illustration of immune cell opening as if on hinge and boxing glove coming out.
New Approach Could Boost Immunotherapy for Breast Cancer
A protein on certain immune cells is a promising target for making immunotherapy more effective against breast cancer.
Science Byte
T cell with on switch
The Warburg Effect: What Turns T Cells On?
Scientists have uncovered a surprising link between metabolism and gene control in T cells.
In the Lab
a sneaky man on a sneaky mission
Stealth Mode: How Metastatic Cancer Cells Evade Detection by the Immune System
Cancer cells have a sneaky ability to hide out in the body for years at a time. MSK scientists are looking for ways to flush them out.
In the Lab
photo of Foxo1 protein stained in regulatory T cells
In the Fight against Cancer, the Immune System Can Be a Double-Edged Sword
The immune system is a powerful tool for fighting cancer — sometimes too powerful.
Q&A
Picturing the Body’s Immune Response
Picturing the Body’s Immune Response
Cell biologist Philipp Niethammer discusses what the zebrafish can teach us about how the body heals.
In the Lab
Pictured: Pseudomonas aeruginosa
The Enemy’s Telltale Mark: Researchers Find Novel Way Body Defends against Harmful Bacteria
MSK researchers discover that the body senses and attacks harmful bacteria indirectly after the pathogens cause stress within the cells.
In the Lab
Pictured: Activated macrophage
Researchers Reveal How Tumors Manipulate Certain Immune Cells to Their Own Advantage
Researchers are exploring a mysterious population of immune cells that live within tumors and can help the cancer grow and spread.
In the Lab
Mouse glioblastoma tumor with phagocytic macrophages
Immune Cells in the Brain Could be Enlisted to Fight Glioblastoma
Memorial Sloan Kettering researchers say a drug that acts on noncancerous, tumor-infiltrating cells might provide a new treatment option for the most common and aggressive type of brain cancer.