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In the Lab
Pictured: Johanna Joyce
Researchers Find Clues to How Breast Cancer Can Infiltrate the Brain

A new study sheds light on what enables breast cancer cells to spread to the brain and presents a potential target for drugs.
In the Lab
Lab mouse with cultured human pluripotent stem cells
A New Mouse? Genetically Pliable Stem Cells Could Advance Research on Many Diseases

Memorial Sloan Kettering researchers have developed a powerful new way to study human disease using stem cells whose genomes can be manipulated at will.
Decoder
Pictured: Gum ball machines
What Is Tumor Heterogeneity?

Understanding tumor heterogeneity may be the next big quest in cancer science, as differences between cells within a tumor can have important consequences for how cancers are diagnosed and treated.
In the Lab
Pictured: Activated macrophage
Researchers Reveal How Tumors Manipulate Certain Immune Cells to Their Own Advantage

Researchers are exploring a mysterious population of immune cells that live within tumors and can help the cancer grow and spread.
Feature
Pictured: Macrophage & Tumor Cells
Turning to Bacteria for Cancer Clues

Approaches used for research into the social lives of bacteria can also be used to explore how tumors behave and evolve.
Decoder
Blood vessels supply tumors with the nutrients they need to grow.
What Is Angiogenesis?

Cancer biologist Robert Benezra explains angiogenesis, the process by which new blood vessels form, and how it relates to cancer research.
In the Lab
Pictured: Cancer cell on blood vessel
Holding On and Hiding Out: How Cancer Cells Spread to the Brain and Thrive

Researchers have gained new understanding of how tumors metastasize by studying the behavior of exceptional breast and lung cancer cells that are capable of entering the brain and surviving there.
In the Lab
Pictured: Charles L. Sawyers, William Polkinghorn & Simon Powell
Molecular Studies Explain Effectiveness of Longtime Treatment for Prostate Cancer

Laboratory studies have revealed an explanation for why androgen-deprivation therapy makes radiation therapy more effective in the treatment of high-risk prostate cancer.
In the Lab
The 1986 explosion at the Chernobyl nuclear power plant released radioactive particles in every direction.
Study Reveals Genetic Causes for Thyroid Cancer Increase after Chernobyl

The study of some victims exposed to ionizing radiation from the 1986 Chernobyl nuclear power plant accident is yielding new information about how radiation-induced thyroid cancer develops.
In the Lab
Mouse glioblastoma tumor with phagocytic macrophages
Immune Cells in the Brain Could be Enlisted to Fight Glioblastoma

Memorial Sloan Kettering researchers say a drug that acts on noncancerous, tumor-infiltrating cells might provide a new treatment option for the most common and aggressive type of brain cancer.