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In the Lab

Prostate Cancer Drug Could Protect Bone Marrow from Damage Caused by Radiation

Researchers are working on a novel method for addressing a common complication of cancer treatment — bone marrow suppression.

Cross sections of mouse femurs showing bone marrow after radiation and no drug (left) and after radiation plus drug (right).

In the Lab

When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.

Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh

Science Byte

Insight into How Lungs Repel Infection Could Guide Therapies for Transplant Patients

Learn how immune cells in the lungs trigger invasive fungal cells to self-destruct. The discovery could produce therapies to prevent infection in cancer patients.

Petri dish with green mold on it

Finding

Is Neurodegenerative Disease a Kind of Cancer?

New findings from experiments done in mice suggest a surprising cause of common neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

A network of neurons

In the Lab

Why Immune Cells Sometimes Fail to Fight Cancer (and What to Do about It)

By looking at how DNA is packaged in cells, scientists are teasing apart a long-standing conundrum about the immune response to cancer.

Scientists at the Sloan Kettering Institute are learning why some immune cells are stubbornly hard to revive with immunotherapy.

In the Lab

CRISPR Genome-Editing Tool Takes Cancer Immunotherapy to the Next Level

What do you get when you combine two of the hottest areas of biotechnology? A new paper from MSK researchers explains.

CAR T cells attacking cancer

In the Lab

Researchers Gain Insight into How a Drug Fires Up an Immune Response to Cancer

Scientists have learned that a drug activates a form of highly inflammatory programmed cell death called pyroptosis — a discovery that sheds light on immune function.

Image of fireball-type explosion on black background.

Q&A

New Approach Could Boost Immunotherapy for Breast Cancer

A protein on certain immune cells is a promising target for making immunotherapy more effective against breast cancer.

Illustration of immune cell opening as if on hinge and boxing glove coming out.

The Warburg Effect: What Turns T Cells On?

Scientists have uncovered a surprising link between metabolism and gene control in T cells.

  • Monday, November 7, 2016

In the Lab

Stealth Mode: How Metastatic Cancer Cells Evade Detection by the Immune System

Cancer cells have a sneaky ability to hide out in the body for years at a time. MSK scientists are looking for ways to flush them out.

a sneaky man on a sneaky mission