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30 News Items found
In the Lab
Illustration of mechanical arms altering a cell
MSK Scientists Fine-Tune CAR T Cells to Improve Their Performance

The updated versions can survive longer in the body while still packing a punch against cancer.
In the Lab
a cabinet full of yellow rubber duckies and one blue one
The Immune System Can Fight Cancer. So Why Doesn’t It?

New research from scientists at the Sloan Kettering Institute helps explain how growing tumors escape our immune defenses.
Finding
Blue cancer cell with a target on it
Adding Low-Dose Radiation Could Make CAR T Therapy More Effective, Study Finds

The treatment combination appears to boost chimeric antigen receptor (CAR) T cells’ ability to kill cancer cells in solid tumors.
In the Lab
Different viewpoints of the STING pathway
Putting the STING in Immunotherapy: Research Focuses on Ways to Improve Cancer Treatments

Researchers are looking for ways to make cancer cells more visible to the immune system.
Finding
Scanning electron micrograph (SEM) of T lymphocyte cells (blue) attached to a red cancer cell.
Discovery of Unusual Cell Type Could Help Guide Immunotherapy

A newly identified group of immunosuppressive cells could provide insight into the effects of immunotherapy drugs.
In the Clinic
Medical oncologist Jae Park
Longest-Running CAR T Trial Shows Which Patients Benefit Most, Have Fewest Side Effects

The study represents 20 years of research at MSK.
In the Clinic
MSK medical oncologist Luis Diaz, Jr.
The Science Behind the FDA’s Approval of an Immunotherapy for Mismatch Repair–Deficient Cancers

A new paper from MSK physician-scientist Luis Diaz presents the evidence on which the FDA approved the immunotherapy drug pembrolizumab for cancers with a specific genetic abnormality.
In the Lab
Scientists at the Sloan Kettering Institute are learning why some immune cells are stubbornly hard to revive with immunotherapy.
Why Immune Cells Sometimes Fail to Fight Cancer (and What to Do about It)

By looking at how DNA is packaged in cells, scientists are teasing apart a long-standing conundrum about the immune response to cancer.
Q&A
Illustration of immune cell opening as if on hinge and boxing glove coming out.
New Approach Could Boost Immunotherapy for Breast Cancer

A protein on certain immune cells is a promising target for making immunotherapy more effective against breast cancer.
Science Byte
T cell with on switch
The Warburg Effect: What Turns T Cells On?

Scientists have uncovered a surprising link between metabolism and gene control in T cells.