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25 News Items found

In the Clinic

The Science Behind the FDA’s Approval of an Immunotherapy for Mismatch Repair–Deficient Cancers

A new paper from MSK physician-scientist Luis Diaz presents the evidence on which the FDA approved the immunotherapy drug pembrolizumab for cancers with a specific genetic abnormality.

MSK medical oncologist Luis Diaz, Jr.

In the News

#ASCO17: Post-Conference Roundup of Themes and Trends

Read up on the progress being made in several key areas of cancer research, including immunotherapy, targeted therapy, precision surgery, and epigenetics.

American Society of Clinical Oncology logo

In the Lab

CRISPR Genome-Editing Tool Takes Cancer Immunotherapy to the Next Level

What do you get when you combine two of the hottest areas of biotechnology? A new paper from MSK researchers explains.

CAR T cells attacking cancer

In the Lab

Stealth Mode: How Metastatic Cancer Cells Evade Detection by the Immune System

Cancer cells have a sneaky ability to hide out in the body for years at a time. MSK scientists are looking for ways to flush them out.

a sneaky man on a sneaky mission

In the Lab

In the Fight against Cancer, the Immune System Can Be a Double-Edged Sword

The immune system is a powerful tool for fighting cancer — sometimes too powerful.

photo of Foxo1 protein stained in regulatory T cells

In the Clinic

Report Highlights Advances Made at MSK That Are Changing Patients’ Lives

An annual report from an influential cancer group highlights three MSK studies that have advanced cancer research.

New treatments developed at MSK focus on both common and rare cancers.

In the Lab

New Findings Clarify How Immunotherapy Works — and Why, In Some People, It Doesn’t

In people with melanoma who respond to the drug ipilimumab, certain mutations make tumors more visible to the immune system.

Pictured: Jedd Wolchok, Alexandra Snyder Charen and Timothy Chan

Finding

Immunotherapy Shows Promise for Treating Solid Tumors in the Chest

A study in mouse models suggests how modified T cells may be used to treat tumors in the area just outside the lungs.

Michel Sadelain and Prasad Adusumilli

In the Lab

Genetic “Kill Switch” Could Make Cell Therapies Safer

Researchers have engineered a gene into therapeutic cells that allows them to turn off tumor growth if some of the cells become cancerous.

Pictured: Experimental Brain Tumor

In the News

Cancer Immunotherapy Named Science Magazine “Breakthrough of the Year”

Memorial Sloan Kettering researchers have played a major role in cancer immunotherapy research, named “Breakthrough of the Year” by Science magazine.

Pictured: T cells