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17 News Items found

In the Lab

In a Twist, Scientists Find Cancer Drivers Hiding in RNA, Not DNA

New findings from researchers at the Sloan Kettering Institute suggest that cancer causes may be lurking in the molecule that bridges DNA and protein.

Sloan Kettering Institute molecular biologist Christine Mayr

In the Lab

MSK Scientists Build "Armored" CAR T Cells to Smite Solid Tumors

The engineered immune cells secrete powerful drugs as a layer of defense.

MSK physician-scientist Renier Brentjens

In the Lab

Scientists Identify Growth Signal for Metastatic Cancer "Seeds"

Targeting this signal with drugs might be one way to stop cancers from spreading.

This image shows cancer cells (white) and pericytes (green) clinging to capillaries (red). The blue dots are nuclei.

Feature

Meet the Scientists Who Engineer CAR T Cells, a Type of "Living" Immunotherapy

An immunotherapy called CAR T is transforming the treatment of certain cancers. These are the people who make it possible.

MSK cell manufacturing specialist Xiuyan Wang

Feature

Meet the Unsung Immune Cell that Could Change Immunotherapy

A lesser-known immune cell is suddenly getting more attention in the field of cancer immunology.

NK cells attacking

Finding

Don't Scratch That Mole? Scientists Are Learning More about Inflammation and Cancer

It's not only what's inside your cells that determines your cancer risk. It's what surrounds them too.

A doctor examines a mole.

Feature

What Is Epigenetics, and Why Is Everyone Talking about It?

Epigenetics is frequently in the news, but there's lots of confusion about just what it entails.

A calico cat

Finding

Cancer Cells Eat Fat to Grow and Spread

Research conducted in zebrafish shows that melanoma cells have an affinity for fat, and that eating it makes them more aggressive.

Large cells filled with yellow-colored fat

In the Clinic

CAR Therapy for Solid Tumors Passes Early Milestone

Preliminary results from a clinical trial indicate that an experimental CAR therapy for mesothelioma is safe.

Immunofluorescence staining of human lung cancer showing mesothelin (pink) on cancer cells and human T cells (green).

In the Lab

Neutrophil Recruitment — What's Damage Got to Do with It?

Immune cells called neutrophils are the first responders to sites of infection. A new study probes what gets them there.

Wounding a zebrafish tail fin triggers a wave of calcium that signals damage and recruits neutrophils