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In the Lab
black and white image of cells under a microscope
Researchers Discover Stem Cells That May Drive Aggressive Behavior in Glioblastoma
Researchers have discovered uncanny similarities between cells found in brain tumors and a type of stem cell that’s important for building the brain during fetal development.
In the Lab
Enhanced MRI of a glioblastoma
Starving Cancer Stem Cells Could Be the Trick to Treating Glioblastoma, Study Finds
MSK researchers have identified a compound that kills glioblastoma cells using a mechanism that’s completely different from earlier treatments.
In the Lab
Fibrous extensions of a nerve cell (red) and an oligodendrocyte (green) growing on top of the nerve cell
Can Stem Cells Be Taught to Repair a Radiation-Damaged Brain?
In a recent study, Memorial Sloan Kettering scientists used stem-cell engineering to repair brain injuries in rats. The results raise hope for future therapies that could prevent or fix nerve damage in cancer patients who need brain radiation.
In the Lab
Neurons created from embryonic stem cells
Seeing the Light: How Engineered Nerve Cells Might Curb Parkinson’s Disease
A new tool called optogenetics is revealing clues about the function of a promising experimental therapy derived from stem cells.
In the Lab
Pictured: Ping Chi
Molecular Studies Provide New Clues about Rare Soft Tissue Sarcoma
Genetic analysis reveals biomarkers and possible drug targets for malignant peripheral nerve sheath tumors.
In the Lab
Pictured: Experimental Brain Tumor
Genetic “Kill Switch” Could Make Cell Therapies Safer
Researchers have engineered a gene into therapeutic cells that allows them to turn off tumor growth if some of the cells become cancerous.
In the Lab
Pictured: Cancer cell on blood vessel
Holding On and Hiding Out: How Cancer Cells Spread to the Brain and Thrive
Researchers have gained new understanding of how tumors metastasize by studying the behavior of exceptional breast and lung cancer cells that are capable of entering the brain and surviving there.
In the Lab
Pictured: Stem cell-derived nerve cells exposed to progerin
Researchers Fast-Forward Stem Cell Aging to Study Degenerative Diseases
A team of Memorial Sloan Kettering scientists has come up with an approach to make stem-cell-derived neurons rapidly age in a cell culture dish. The breakthrough could transform research into Parkinson’s and other late-onset diseases.
In the Lab
Mouse glioblastoma tumor with phagocytic macrophages
Immune Cells in the Brain Could be Enlisted to Fight Glioblastoma
Memorial Sloan Kettering researchers say a drug that acts on noncancerous, tumor-infiltrating cells might provide a new treatment option for the most common and aggressive type of brain cancer.
In the Lab
Pictured: Neurons
Researchers Identify Key Element of Nerve Cell Development
Researchers have clarified the process by which developing nerve cells are directed to specialize into distinct parts.