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Feature
Two gloved hands opening a drawer in a laboratory.
Double Trouble: Researchers Find Many Cancers Carry Two Mutations in the Same Gene

Discovery reveals that the genetic causes of cancer may be more complicated than previously thought.
Science Byte
Prostate cancer cells, colored red in scanning electron micrograph (SEM).
PSMA: A New Target for Prostate Cancer Treatment

Researchers have discovered how a high level of the protein PSMA in cells helps fuel prostate cancer.
Feature
Barry Taylor
With MSK Leading the Way, Precision Medicine Links Lab Research to Patient Care

Therapies that target genetic alterations in tumors are showing promise for many cancer patients, but challenges in developing these new treatments remain.
Finding
MSK investigators Michael Berger and David Solit.
Study Reveals How Some Breast Cancers Become Resistant to Targeted Drugs

A study of one patient’s disease has clarified why tumors stop responding to a class of experimental drugs called PI3K inhibitors.
In the Lab
Pictured: Ping Chi
Molecular Studies Provide New Clues about Rare Soft Tissue Sarcoma

Genetic analysis reveals biomarkers and possible drug targets for malignant peripheral nerve sheath tumors.
In the Lab
Pictured: Scott Lowe
Researchers Uncover Potential Target for “Undruggable” Form of Liver Cancer

In taking a new approach to finding treatments for hepatocellular carcinoma, MSK scientists have uncovered a potential drug target for this highly aggressive cancer.
Decoder
Pictured: Gum ball machines
What Is Tumor Heterogeneity?

Understanding tumor heterogeneity may be the next big quest in cancer science, as differences between cells within a tumor can have important consequences for how cancers are diagnosed and treated.
Announcement
Pictured: José Baselga, Agnès Viale, Michael Berger & David Solit
Bold Initiative to Transform Cancer Care Established with a $100 Million Gift

With the creation of the Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering sets out to deliver on the promise of personalized medicine by creating better treatment options for all people with cancer.
Snapshot
Breast cancer mosaic
New Technology Could Enable Immediate Detection of Tumor Borders during Surgery

Memorial Sloan Kettering scientists are developing new imaging instrumentation that could enable pathologist and surgeons to collaborate more seamlessly and reduce the need for repeat surgeries.
Researchers Find Genetic Key to Breast Cancer's Ability to Survive and Spread

New research led by investigators at Memorial Sloan Kettering Cancer Center sheds light on a genetic function that gives breast cancer cells the ability to survive and spread to the bone years after treatment has been administered.