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Q&A
Michel Talagrand, Maria Jasin, Carrie Lam Cheng Yuet-ngor, and Edward Stone
Meet Maria Jasin, an Award-Winning Biologist Who Studies DNA Repair

Maria Jasin, a member of the Sloan Kettering Institute’s Developmental Biology Program, discusses her research.
In the Lab
An illustration of proteins serving as bar-code-reading drones
“Molecular Origami” Enables Proteins to Serve as Specialized Delivery Vehicles, Study Finds

Scientists at the Sloan Kettering Institute have identified a fundamentally new type of protein-sorting system in cells.
Feature
an illustration of a cigarette burning and smoke entering lungs
How Do Cigarettes Cause Cancer?

Everyone knows that cigarettes cause cancer. But what do we know about how they do it?
Science Byte
Cancer biologist and pediatric oncologist Alex Kentsis
Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers

A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.
In the Clinic
Image of DNA helix with sequence in the background
Genetic ‘Scars’ Provide Clues for Tailoring Cancer Treatment

For the first time, scientists have determined the extent of DNA repair deficiencies across cancer types. Learn what it means for patients.
Science Byte
Blue cells containing small red dots on a green and black background
Lifeguard on Duty: Looking at DNA Repair under a Microscope

Learn about what DNA repair looks like under a microscope.
In the Lab
Cancer biologist and pediatric oncologist Alex Kentsis
Jumping Genes and the Dark Genome: MSK Researchers Gain New Insight into Childhood Cancers

Researchers have discovered a genetic mechanism that may trigger most childhood cancers.
In the Lab
A cell in the process of dividing
New Study Shows How Wayward Chromosomes Get Back on Track

MSK researchers are learning how cells are able to recognize and correct errors that occur during cell division.
Feature
Molecular biologist John Petrini of the Sloan Kettering Institute.
Understanding the DNA-Damage “First Responders”: John Petrini at Work

Scientists know that cancer can result from mistakes in DNA repair. But understanding what controls the repair process itself has been a hard nut to crack.
Science Byte
Illustration of DNA with green wrench making adjustments to a nut on the double helix.
A Clean Break: Scientists Make Surprising Discoveries about DNA Repair

A study reveals unexpected insights into how cells prepare broken DNA strands to be rejoined, preventing mutations that can cause cancer.