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54 News Items found

In the Lab

Scientists Identify Growth Signal for Metastatic Cancer "Seeds"

Targeting this signal with drugs might be one way to stop cancers from spreading.

This image shows cancer cells (white) and pericytes (green) clinging to capillaries (red). The blue dots are nuclei.

In the Lab

With Help of CRISPR, Scientists Unravel the Cause of a Rare Liver Cancer

A team led by MSK molecular biologist Scott Lowe is making progress against fibrolamellar hepatocellular carcinoma.

A microscopic view of genetically engineered mouse tumor and a human FL-HCC tumor

Science Byte

Blocking Enzymes That Signal DNA Damage Could Be a Treatment Strategy for Childhood Cancers

A new strategy for treating pediatric cancers involves preventing cells from repairing their own DNA.

Graphic of shattered, red, DNA double-helix

Finding

Making an IMPACT: MSK’s Gene-Sequencing Test Reveals New Findings about Hereditary Cancer Risk

An analysis of germline DNA in people with advanced cancer finds that inherited mutations may be more common than expected in this group.

Kenneth Offit and Vijai Joseph

In the Lab

When Loss Is a Gain: New Tumor Suppressor Gene Identified in Follicular Lymphoma

The reason certain patients with follicular lymphoma do worse than others may come down to a missing gene.

A scientist looks at illustrations of chromosomes.

In the Clinic

The Science Behind the FDA’s Approval of an Immunotherapy for Mismatch Repair–Deficient Cancers

A new paper from MSK physician-scientist Luis Diaz presents the evidence on which the FDA approved the immunotherapy drug pembrolizumab for cancers with a specific genetic abnormality.

MSK medical oncologist Luis Diaz, Jr.

Science Byte

Lifeguard on Duty: Looking at DNA Repair under a Microscope

Learn about what DNA repair looks like under a microscope.

Blue cells containing small red dots on a green and black background

in the Lab

Jumping Genes and the Dark Genome: MSK Researchers Gain New Insight into Childhood Cancers

Researchers have discovered a genetic mechanism that may trigger most childhood cancers.

Cartoon illustration of DNA double-helix segment (with arms and legs) “jumping” to from one part of the double-helix to another.

Making a Splash: Researchers Apply Face-Detection Technology to the Study of Genes

Taking a cue from smartphone technology, scientists are using face-recognition algorithms to improve RNA interference.

Mount Rushmore viewed through face-detection software.

In the Lab

A Cut Above: MSK-Developed Software Makes CRISPR More Precise

A freely accessible software program provides researchers with an easy way to optimize a popular genome-editing tool.

An illustration of CRISPR-Cas9