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65 News Items found
In the Lab
Cancer biologist Scott Lowe
Drug Combination Could Boost the Effectiveness of Immunotherapy against Pancreatic Cancer

Studies conducted in mice reveal a potential way to breach the defenses of pancreatic cancer tumors.
Finding
Illustration of Enterococcus
Study in Mice Suggests Lactose in the Diet Feeds Dangerous Gut Bacteria When the Immune System Is Compromised

Lab mice who had lactose removed from their diets had a decreased risk of infection with the Enterococcus bacterium.
In the Lab
Illustration of how PU-PET localizes to tumors
Bull’s-Eye: Imaging Technology Could Confirm When a Drug Is Going to the Right Place

Collaborative team advances a new approach for imaging a drug that’s been developed to stop cancer growth.
In the Lab
a colorful dendritic cell
Newly Discovered Immune Cell Subtypes Could Shake Up Immunotherapy

Dendritic cells, the guards of the immune system, have a previously unrecognized division of labor.
In the Lab
Cancer biologist and pediatric oncologist Alex Kentsis
Analyzing Urine Can Guide the Treatment of Childhood Kidney Tumors

A protein detected in the urine of children with Wilms’ tumor led to the development of a test to improve diagnosis and treatment.
Finding
Computational biologist Barry Taylor
Whether a BRCA Mutation Leads to Cancer Depends on Context, Study Finds

Sometimes a BRCA mutation is just along for the ride, rather than driving a tumor’s development.
In the Lab
MSK cancer researchers Elizabeth Adams, Charles Sawyers, and Rohit Bose
Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype

Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found.
Finding
Drawing of one human figure set apart from a group of others.
One Patient’s Exceptional Response Leads to a Surprising Discovery about Immunotherapy

MSK researchers learn that some cancers may respond to checkpoint inhibitor drugs because of changes called gene fusions.
Feature
Model of TGF-beta molecule
An Old Protein Gets a New Look: Researchers Target TGF-ß to Make Immunotherapy More Effective

Drugs that block the action of TGF-ß may make checkpoint inhibitors more effective.
In the Clinic
Scientific Image
CAR Therapy for Solid Tumors Draws Attention at Annual Cancer Conference

Results from a clinical trial indicate that an experimental CAR therapy for mesothelioma is safe.