Recent News: Targeted Therapy

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30 News Items found

In the Lab

Drug Combination Could Boost the Effectiveness of Immunotherapy against Pancreatic Cancer

By Matthew Tontonoz

Studies conducted in mice reveal a potential way to breach the defenses of pancreatic cancer tumors.

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A drawing of a pancreatic tumor represented as a barren landscape, blood vessels as rivers, and immune cells as ships with ammunition.

In the Lab

Bull’s-Eye: Imaging Technology Could Confirm When a Drug Is Going to the Right Place

By Julie Grisham

Collaborative team advances a new approach for imaging a drug that’s been developed to stop cancer growth.

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Illustration of how PU-PET localizes to tumors

Finding

Whether a BRCA Mutation Leads to Cancer Depends on Context, Study Finds

By Matthew Tontonoz

Sometimes a BRCA mutation is just along for the ride, rather than driving a tumor’s development.

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Computational biologist Barry Taylor

In the Lab

Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype

By Matthew Tontonoz

Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found.

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MSK cancer researchers Elizabeth Adams, Charles Sawyers, and Rohit Bose

Feature

An Old Protein Gets a New Look: Researchers Target TGF-ß to Make Immunotherapy More Effective

By Julie Grisham

Drugs that block the action of TGF-ß may make checkpoint inhibitors more effective.

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Model of TGF-beta molecule

Finding

Research Uncovers the Genetic Causes of Aggressive Leukemia in Children

By Julie Grisham

Researchers have found that the genetic changes that cause pediatric leukemia are different from those that lead to leukemia in adults.

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Alex Kentsis in his lab

In the Clinic

Analyzing Spinal Fluid Could Guide Brain Tumor Diagnosis and Treatment

By Jim Stallard

Cancer DNA taken from spinal fluid could serve as a liquid biopsy that provides information on brain tumor mutations.

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MRI of brain and spinal fluid in green

Roundup

Top 10 Stories of 2018, Cancer Research Edition

By Matthew Tontonoz

Take a look back at some of the year’s biggest news in cancer research.

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2018

In the Clinic

Liquid Biopsy Is Effective at Guiding Treatment of Lung Cancer, Study Finds

By Matthew Tontonoz

The initial results of an ongoing study show that a liquid biopsy has advantages over a tissue biopsy for people with lung cancer.

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A tube of blood superimposed on a lung and a DNA helix

In the Lab

Scientists Pinpoint a New Cause of Resistance to EGFR-Targeting Drugs

By Matthew Tontonoz

Multiple copies of a gene called YES1 appear to be responsible for certain precision drugs losing their effectiveness.

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Blue cells containing small red and green dots on a black background