Recent News: Metastasis & Drug Resistance

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21 News Items found

In the Lab

What Does Cancer Metastasis Have to Do with Wound Healing? More than You Might Think

Scientists are learning that — in a literal sense — metastasis is wound healing gone wrong.

Graphical representation of cells leaking into bloodstream

In the Lab

Mind the Gap: Scientists Learn How Cells Make and Repair Tight Connections

New findings from researchers at the Sloan Kettering Institute provide insight into a fundamental biological process called the epithelial-mesenchymal transition.

Epithelial cells

In the Lab

Scientists Identify Growth Signal for Metastatic Cancer "Seeds"

Targeting this signal with drugs might be one way to stop cancers from spreading.

This image shows cancer cells (white) and pericytes (green) clinging to capillaries (red). The blue dots are nuclei.

In the Lab

When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.

Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh

In the Lab

Stealth Mode: How Metastatic Cancer Cells Evade Detection by the Immune System

Cancer cells have a sneaky ability to hide out in the body for years at a time. MSK scientists are looking for ways to flush them out.

a sneaky man on a sneaky mission

In the Lab

Studying Cancer Mysteries Just Beneath the Scales

Hail to the zebrafish. MSK scientists are using a small fish to answer some big questions about cancer.

Pictured: Casper zebrafish

In the Lab

Outsmarting Cancer’s Survival Skills

A new study led by MSK investigators reveals how some cancer cells become resistant to targeted treatment and suggests what might be done to stop that from happening.

MSK investigators Joan Massagué and Anna Obenauf

Finding

Study Reveals How Some Breast Cancers Become Resistant to Targeted Drugs

A study of one patient’s disease has clarified why tumors stop responding to a class of experimental drugs called PI3K inhibitors.

MSK investigators Michael Berger and David Solit.

In the Lab

Researchers Uncover Potential Target for “Undruggable” Form of Liver Cancer

In taking a new approach to finding treatments for hepatocellular carcinoma, MSK scientists have uncovered a potential drug target for this highly aggressive cancer.

Pictured: Scott Lowe

In the Lab

Researchers Find Clues to How Breast Cancer Can Infiltrate the Brain

A new study sheds light on what enables breast cancer cells to spread to the brain and presents a potential target for drugs.

Pictured: Johanna Joyce