Recent News: Lab Research

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148 News Items found
In the Lab
An illustration of sugar being sprinkled on a cancer cell.
Just Add Sugar: How a Protein’s Small Change Leads to Big Trouble for Cells

By Julie Grisham

A study from investigators in the Sloan Kettering Institute uncovers the details of how a key protein called GRP94 becomes disrupted, leading to cancer and other diseases.
Tags: Sloan Kettering Institute · Chemical Biology · Discoveries & Advances · Lab Research · Targeted Therapy
In the Lab
Confocal microscopy image of a female fruit fly brain.
How Fruit Flies Know When They've Mated

By Matthew Tontonoz

Research from investigators at the Sloan Kettering Institute shows how a brain circuit controls mating behavior in fruit flies.
Tags: Developmental Biology · Discoveries & Advances · Lab Research
In the Lab
CT scan showing lymphoma in the abdomen between the liver and the gallbladder.
A Metabolic Enzyme Drives Lymphoma and Is a Potential Drug Target

By Matthew Tontonoz

New research from Sloan Kettering Institute investigators pinpoints altered cell metabolism as a cause of B cell lymphoma.
Tags: Research · Cancer Genetics & Genomics · Cancer Metabolism · Discoveries & Advances · Lab Research
In the Lab
X and Y chromosomes in mice
Breaking Up Is Hard to Do (Especially for Sex Chromosomes)

By Matthew Tontonoz

One’s big, one’s small. Somehow, they make it work.
Tags: Discoveries & Advances · Lab Research
Feature
Two gloved hands opening a drawer in a laboratory.
Double Trouble: Researchers Find Many Cancers Carry Two Mutations in the Same Gene

By Julie Grisham

Discovery reveals that the genetic causes of cancer may be more complicated than previously thought.
Tags: Computational Oncology · Discoveries & Advances · Lab Research · Molecular Pathology & Diagnostics
In Brief
A fluorescent image of cells undergoing differentiation in a mouse model.
Cancer Stem Cells’ Reliance on a Key Amino Acid Could Be an Exploitable Weakness

By Matthew Tontonoz

The discovery links metabolism to the way cancer stem cells form tumors.
Tags: Cancer Metabolism · Discoveries & Advances · Lab Research
In the Lab
Chromosomes from a human male
How Small Chromosomes Compete with Big Ones for a Cell’s Attention

By Matthew Tontonoz

During meiosis, small chromosomes risk being lost in the shuffle. Here’s how they hold their own.
Tags: Discoveries & Advances · Lab Research
In the Lab
Fluorescent image of mouse prostate gland
New Discovery Explains How the Prostate Gland Regenerates Itself

By Matthew Tontonoz

Androgen-deprivation therapy, a mainstay of prostate cancer treatment, may give prostate cells new growth abilities, scientists at Memorial Sloan Kettering have found.
Tags: Discoveries & Advances · Lab Research · Solid Tumor Oncogenesis
In the Lab
An illustration of a samurai riding a horse along a strand of RNA. The samurai’s sword is changing the letter A to the letter I.
Novel Tool Enables Study of Rare Acute Myeloid Leukemia Stem Cells

By Julie Grisham

MSK investigators have used a lab tool originally developed to study fly nerve cells to uncover new findings about acute myeloid leukemia.
Tags: Sloan Kettering Institute · Discoveries & Advances · Lab Research · Hematologic Malignancies · Targeted Therapy
In the Lab
Bacteroides bacteria under the microscope
Research Uncovers Details about How Gut Microbes Influence the Immune System

By Julie Grisham

Investigators have shown how gut microbes promote the formation of a type of immune cell called regulatory T cells.
Tags: Sloan Kettering Institute · Cancer Immunotherapy & Vaccines · Discoveries & Advances · Lab Research · Immunology · Microbiome & Inflammation