Recent News: Lab Research

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137 News Items found

In the Lab

Shape-Shifting Stem Cells Are Key to Cancer Metastasis and Immune Evasion

By Matthew Tontonoz

By assuming primitive regenerative identities, cancer cells gain the adaptability they need to establish tumors in new parts of the body.

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An illustration of lung develop alongside tumor evolution

Feature

Researchers Find that Vitamin B6 Contributes to Survival of Acute Myeloid Leukemia Cells

By Julie Grisham

This research marks the first time researchers have found a connection between vitamin B6 and cancer.

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Cancer biologist Scott Lowe at a white board

In the Lab

What Does Cancer Metastasis Have to Do with Wound Healing? More than You Might Think

By Matthew Tontonoz

Scientists are learning that — in a literal sense — metastasis is wound healing gone wrong.

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Graphical representation of cells leaking into bloodstream

In the Lab

Mind the Gap: Scientists Learn How Cells Make and Repair Tight Connections

By Matthew Tontonoz

New findings from researchers at the Sloan Kettering Institute provide insight into a fundamental biological process called the epithelial-mesenchymal transition.

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Epithelial cells

In the Lab

Why KRAS Inhibitors for Lung Cancer Stop Working (and What Can Be Done about It)

By Matthew Tontonoz

Recently developed targeted drugs used to treat lung cancer are only partially effective. Scientists now know why.

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A picture of KRAS-mutated lung cancer cells

Finding

Many Mutations Detected in Liquid Biopsy Tests Do Not Come from Cancer Cells, an MSK Study Finds

By Matthew Tontonoz

The new findings suggest the need for caution when interpreting the results from these tests.

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Pedram Razavi, Jorge Reis-Filho, and Bob Li

In the Lab

One at a Time: New Tool Can Detect Genetic Changes in Thousands of Single Cancer Cells

By Matthew Tontonoz

Developed by scientists at MSK and the University of British Columbia/BC Cancer, the platform provides the deepest look yet into tumor evolution.

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DLP+ in action

In the Lab

Newly Discovered Immune Cell Subtypes Could Shake Up Immunotherapy

By Matthew Tontonoz

Dendritic cells, the guards of the immune system, have a previously unrecognized division of labor.

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a colorful dendritic cell

In the Lab

New Findings Clarify How the “Guardian of the Genome” Works

By Matthew Tontonoz

Surprise! It has to do with metabolism.

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illustration of the p53 protein binding to a DNA helix

Finding

Scientists See Potential in Cellular “Death by Iron” for Cancer Treatment

By Matthew Tontonoz

This form of cell death is called ferroptosis, and certain cancer cells are especially vulnerable to it.

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a man holding a shield and sword