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125 News Items found

In the Lab

How Stem Cells Decide Their Fate

By Julie Grisham

Research in blood stem cells has revealed new information about how these cells decide what to become when they divide.

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An illustration of two teapots with liquid flowing into various cups

In the Lab

“Molecular Origami” Enables Proteins to Serve as Specialized Delivery Vehicles, Study Finds

By Matthew Tontonoz

Scientists at the Sloan Kettering Institute have identified a fundamentally new type of protein-sorting system in cells.

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An illustration of proteins serving as bar-code-reading drones

Finding

Sugar Directly Controls a Cancer-Causing Protein, Scientists Find

By Matthew Tontonoz

The discovery suggests a potential new treatment approach for certain cancers.

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An illustration of sugar pouring onto NRF2

In the Lab

Drug That Hits CAR T Snooze Button Can Quiet a Cytokine Storm

By Matthew Tontonoz

An FDA-approved drug used to treat leukemia can serve as a temporary off switch for CAR T cells, MSK scientists have found.

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cartoon of man hitting a snooze button

In the Lab

Scientists Use CRISPR to Learn How Cells Make Decisions

By Matthew Tontonoz

The genome-editing technique uncovered several genes previously not known to influence embryonic development.

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Fluorescent red and green cells

In the Lab

Research Clarifies How IDH Mutations Cause Cancer

By Julie Grisham

The MSK team’s goal was to get at the underlying defects in cells that these mutations cause.

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DNA winding around histones

In the Lab

Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype

By Matthew Tontonoz

Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found.

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MSK cancer researchers Elizabeth Adams, Charles Sawyers, and Rohit Bose

In The Lab

Ro Versus Musashi: How One Molecule Can Turn Cancer Cells Back to Normal

By Julie Grisham

Researchers identify a compound that appears to eliminate tumor cells in a dish and in mice.

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An illustration of a samurai and a crab.

In the Lab

Checkpoint Challenge: When Releasing Immune Cell Brakes Is Not Enough to Stop Cancer

By Matthew Tontonoz

Scientists have learned that cutting a T cell’s brakes can have unexpected consequences.

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Immune cells surrounding a cancer cell

In The Lab

Computational “Hive Mind” Helps Scientists Solve an Enzyme’s Cryptic Movements

By Matthew Tontonoz

The breakthrough gives an unprecedented look at the varied and shifting poses of a protein in action.

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Two clusters of colored blobs with a diagram in the middle