Recent News: Immunotherapy

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Finding

Adding Low-Dose Radiation Could Make CAR T Therapy More Effective, Study Finds

By Matthew Tontonoz Thursday, October 25, 2018

The treatment combination appears to boost chimeric antigen receptor (CAR) T cells’ ability to kill cancer cells in solid tumors.

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In the News

Former MSK Immunologist James Allison Wins Nobel Prize in Medicine

By Matthew Tontonoz Monday, October 1, 2018

Dr. Allison is being honored for discovering how to take the brakes off cancer-fighting immune cells.

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Feature

Meet the Scientists Who Engineer CAR T Cells, a Type of "Living" Immunotherapy

By Matthew Tontonoz Monday, July 23, 2018

An immunotherapy called CAR T is transforming the treatment of certain cancers. These are the people who make it possible.

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MSK cell manufacturing specialist Xiuyan Wang

Finding

Discovery of Unusual Cell Type Could Help Guide Immunotherapy

By Jim Stallard Tuesday, June 12, 2018

A newly identified group of immunosuppressive cells could provide insight into the effects of immunotherapy drugs.

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Scanning electron micrograph (SEM) of T lymphocyte cells (blue) attached to a red cancer cell.

In the Clinic

CAR Therapy for Solid Tumors Passes Early Milestone

By Matthew Tontonoz Thursday, May 17, 2018

Preliminary results from a clinical trial indicate that an experimental CAR therapy for mesothelioma is safe.

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Immunofluorescence staining of human lung cancer showing mesothelin (pink) on cancer cells and human T cells (green).

In the Clinic

Longest-Running CAR T Trial Shows Which Patients Benefit Most, Have Fewest Side Effects

By Matthew Tontonoz Wednesday, January 31, 2018

For adults with chemotherapy-resistant leukemia, CAR T cell therapy can be a lifesaving treatment option. New results suggest how to make it safer.

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In the Lab

Why Do Immune Checkpoint Inhibitors Work for Only Some People with Cancer?

By Julie Grisham Tuesday, October 24, 2017

Learn about why checkpoint inhibitors, a class of immunotherapy drugs,  is paying off — but only for some patients.

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Announcement

FDA Approves First CAR T Cell Therapy for Leukemia

By Matthew Tontonoz Wednesday, August 30, 2017

Children, teens, and young adults with leukemia that have stopped responding to chemotherapy are the first eligible to receive the new treatment.

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Pediatric oncologist Kevin Curran with CAR T patient Esmeralda Pineda

In the Clinic

The Science Behind the FDA’s Approval of an Immunotherapy for Mismatch Repair–Deficient Cancers

By Matthew Tontonoz Friday, June 9, 2017

A new paper from MSK physician-scientist Luis Diaz presents the evidence on which the FDA approved the immunotherapy drug pembrolizumab for cancers with a specific genetic abnormality.

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In the News

#ASCO17: Post-Conference Roundup of Themes and Trends

By Matthew Tontonoz Wednesday, June 7, 2017

Read up on the progress being made in several key areas of cancer research, including immunotherapy, targeted therapy, precision surgery, and epigenetics.

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Adding Low-Dose Radiation Could Make CAR T Therapy More Effective, Study Finds

TAGS:

Former MSK Immunologist James Allison Wins Nobel Prize in Medicine

TAGS:

Meet the Scientists Who Engineer CAR T Cells, a Type of "Living" Immunotherapy

TAGS:

Discovery of Unusual Cell Type Could Help Guide Immunotherapy

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CAR Therapy for Solid Tumors Passes Early Milestone

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Longest-Running CAR T Trial Shows Which Patients Benefit Most, Have Fewest Side Effects

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Why Do Immune Checkpoint Inhibitors Work for Only Some People with Cancer?

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FDA Approves First CAR T Cell Therapy for Leukemia

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The Science Behind the FDA’s Approval of an Immunotherapy for Mismatch Repair–Deficient Cancers

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#ASCO17: Post-Conference Roundup of Themes and Trends

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Liquid Biopsy Is Effective at Guiding Treatment of Lung Cancer, Study Finds

Symposium Celebrates 15 Years of Developmental Biology at the Sloan Kettering Institute

This Newly Discovered Organelle Is Fierce

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