Recent News: Epigenetics

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13 News Items found

In the Lab

Research Clarifies How IDH Mutations Cause Cancer

The MSK team’s goal was to get at the underlying defects in cells that these mutations cause.

DNA winding around histones

In the Lab

Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype

Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found.

MSK cancer researchers Elizabeth Adams, Charles Sawyers, and Rohit Bose

In th Lab

Cellular “Garbage Collectors” Are Key to Cancer’s Growth

A new study suggests a way to target cancer by interfering with its system of waste removal.

A cartoon depicting a cleaning crew

Feature

What Is Epigenetics, and Why Is Everyone Talking about It?

Epigenetics is frequently in the news, but there's lots of confusion about just what it entails.

A calico cat

Announcement

FDA Approves Enasidenib (Idhifa), a First-of-Its-Kind Drug, for Advanced Blood Cancer

A new treatment option for people with acute myeloid leukemia is available, and it works in an unconventional way.

Acute myeloid leukemia cells under a microscope

In the Lab

When Loss Is a Gain: New Tumor Suppressor Gene Identified in Follicular Lymphoma

The reason certain patients with follicular lymphoma do worse than others may come down to a missing gene.

A scientist looks at illustrations of chromosomes.

In the Lab

Why Immune Cells Sometimes Fail to Fight Cancer (and What to Do about It)

By looking at how DNA is packaged in cells, scientists are teasing apart a long-standing conundrum about the immune response to cancer.

Scientists at the Sloan Kettering Institute are learning why some immune cells are stubbornly hard to revive with immunotherapy.

In the Lab

Uncharted Waters: The Making of a New Cancer Drug

A team of scientists is combining sophisticated chemistry and experiments in zebrafish to develop a new cancer drug that shows early potential against melanoma and metastatic breast cancer.

Portrait of a live zebrafish with dark patterning around and above the eyes

In the Lab

Investigators Use Stem Cells to Study Rare Pediatric Brain Tumors

Investigators have created the first-ever genetically engineered model of cancer made from human embryonic stem cells in culture.

Pictured: Viviane Tabar

Decoder

What Is Epigenetics?

Physician-scientist Omar Abdel-Wahab explains epigenetics, a growing field based on the study of genetic changes that are not part of the DNA code, and how it relates to cancer.

DNA wrapped around histones