Recent News: Computational Oncology

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14 News Items found

Finding

Whether a BRCA Mutation Leads to Cancer Depends on Context, Study Finds

Sometimes a BRCA mutation is just along for the ride, rather than driving a tumor’s development.

Computational biologist Barry Taylor discusses findings of a new study about BRCA genes.

In the Lab

Scientists Rewrite the Textbook of Organ Development, One Cell at a Time

A large study that analyzed nearly 120,000 cells in a developing mouse embryo is full of surprises.

In this fluorescent microscopy image of endoderm tissue from a mouse embryo, cell membranes are red, cell nuclei are blue, and extra-embryonic endoderm cells are green (they appear turquoise because blue and green are merged).

In the Lab

Scientists Create First-of-Its-Kind Metabolic Road Map of Cancer

The online resource will serve as a benchmark for researchers studying metabolism and cancer.

abstract red and blue lines suggestive of metabolic pathways

Making a Splash: Researchers Apply Face-Detection Technology to the Study of Genes

Taking a cue from smartphone technology, scientists are using face-recognition algorithms to improve RNA interference.

Mount Rushmore viewed through face-detection software.

In the Lab

A Cut Above: MSK-Developed Software Makes CRISPR More Precise

A freely accessible software program provides researchers with an easy way to optimize a popular genome-editing tool.

An illustration of CRISPR-Cas9

Announcement

Expanding the Impact of Precision Medicine to Fuel Discoveries

MSK’s Functional Genomics Initiative will enable basic scientists to take full advantage of the massive amount of data produced by tumor sequencing.

Christina Leslie and John Petrini

In the Lab

Beyond the Usual Suspects: Study of Noncoding DNA Reveals New Mutations Linked to Cancer

In a study of patient tumor samples, researchers have found common mutations in parts of the genome that control gene regulation.

Pictured: William Lee, Chris Sander & Nils Weinhold

Decoder

What Is Tumor Heterogeneity?

Understanding tumor heterogeneity may be the next big quest in cancer science, as differences between cells within a tumor can have important consequences for how cancers are diagnosed and treated.

Pictured: Gum ball machines

Announcement

Bold Initiative to Transform Cancer Care Established with a $100 Million Gift

With the creation of the Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering sets out to deliver on the promise of personalized medicine by creating better treatment options for all people with cancer.

Pictured: José Baselga, Agnès Viale,  Michael Berger & David Solit

In the Lab

Do Cancer Cell Lines Really Resemble Tumors? Now Researchers Can Tell

A recent study found that the cell lines most commonly used for research on ovarian cancer are not the most suitable.

Pictured: Cancer cell lines