Recent News: Computational Oncology

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16 News Items found
Feature
Two gloved hands opening a drawer in a laboratory.
Double Trouble: Researchers Find Many Cancers Carry Two Mutations in the Same Gene
Discovery reveals that the genetic causes of cancer may be more complicated than previously thought.
In the Lab
DLP+ in action
One at a Time: New Tool Can Detect Genetic Changes in Thousands of Single Cancer Cells
Developed by scientists at MSK and the University of British Columbia/BC Cancer, the platform provides the deepest look yet into tumor evolution.
Finding
Computational biologist Barry Taylor
Whether a BRCA Mutation Leads to Cancer Depends on Context, Study Finds
Sometimes a BRCA mutation is just along for the ride, rather than driving a tumor’s development.
In the Lab
In this fluorescent microscopy image of endoderm tissue from a mouse embryo, cell membranes are red, cell nuclei are blue, and extra-embryonic endoderm cells are green (they appear turquoise because blue and green are merged).
Scientists Rewrite the Textbook of Organ Development, One Cell at a Time
A large study that analyzed nearly 120,000 cells in a developing mouse embryo is full of surprises.
In the Lab
abstract red and blue lines suggestive of metabolic pathways
Scientists Create First-of-Its-Kind Metabolic Road Map of Cancer
The online resource will serve as a benchmark for researchers studying metabolism and cancer.
Mount Rushmore viewed through face-detection software.
Making a Splash: Researchers Apply Face-Detection Technology to the Study of Genes
Taking a cue from smartphone technology, scientists are using face-recognition algorithms to improve RNA interference.
In the Lab
An illustration of CRISPR-Cas9
A Cut Above: MSK-Developed Software Makes CRISPR More Precise
A freely accessible software program provides researchers with an easy way to optimize a popular genome-editing tool.
Announcement
Christina Leslie and John Petrini
Expanding the Impact of Precision Medicine to Fuel Discoveries
MSK’s Functional Genomics Initiative will enable basic scientists to take full advantage of the massive amount of data produced by tumor sequencing.
In the Lab
Pictured: William Lee, Chris Sander & Nils Weinhold
Beyond the Usual Suspects: Study of Noncoding DNA Reveals New Mutations Linked to Cancer
In a study of patient tumor samples, researchers have found common mutations in parts of the genome that control gene regulation.
Decoder
Pictured: Gum ball machines
What Is Tumor Heterogeneity?
Understanding tumor heterogeneity may be the next big quest in cancer science, as differences between cells within a tumor can have important consequences for how cancers are diagnosed and treated.