Recent News: Chemical Biology

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12 News Items found

In The Lab

Computational “Hive Mind” Helps Scientists Solve an Enzyme’s Cryptic Movements

The breakthrough gives an unprecedented look at the varied and shifting poses of a protein in action.

Two clusters of colored blobs with a diagram in the middle

Science Byte

Scientists Discover Keys to Immune Response against Anthrax

Researchers clarify how the immune system activates an inflammatory defense against pathogens.

Ribbon diagram of an anthrax protein.

Feature

Remembering Jerard Hurwitz, a Giant of Molecular Biology

MSK colleagues pay tribute to molecular biologist Jerard Hurwitz’s scientific accomplishments and passion for discovery.

Memorial Sloan Kettering molecular biologist Jerard Hurwitz

In the Lab

Mirror-Image Chemistry Enables New Approach for Targeting an “Undruggable” Cancer-Causing Protein

MSK chemists are focusing on developing small-molecule drugs to target KRas, an important cancer protein.

Left-handed and right-handed KRas molecules

In the Lab

Researchers Gain Insight into How a Drug Fires Up an Immune Response to Cancer

Scientists have learned that a drug activates a form of highly inflammatory programmed cell death called pyroptosis — a discovery that sheds light on immune function.

Image of fireball-type explosion on black background.

In the Lab

Uncharted Waters: The Making of a New Cancer Drug

A team of scientists is combining sophisticated chemistry and experiments in zebrafish to develop a new cancer drug that shows early potential against melanoma and metastatic breast cancer.

Portrait of a live zebrafish with dark patterning around and above the eyes

In the Lab

Miniature Device Could Unlock the Promise of Some Kidney Cancer Drugs

Memorial Sloan Kettering scientists have engineered a tiny particle that could ferry drugs directly to the kidneys and prevent their uptake in other organs.

Proximal tubule of the kidney.

Finding

Hsp90: A Very Promising Target for Cancer Therapy

A small molecule discovered at MSK called PU-H71 blocks the growth of cancer cells and enables doctors to image tumors.

Pictured: Gabriela Chiosis

Video

Tiny Solutions for Big Problems: A Visit to the Lab of Daniel Heller

Learn about Daniel Heller, who creates new nanoscale materials that are specially designed to improve biological research or solve clinical problems.

Pictured: Daniel Heller

Q&A

Taking Clues from Nature for the Development of New Drugs

In this Q&A, Memorial Sloan Kettering chemist Derek Tan discusses why natural products offer inspiration for the development of new drugs.

Pictured: Derek Tan