Recent News: Cancer Genetics & Genomics

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66 News Items found

In the Lab

New Findings Clarify How the “Guardian of the Genome” Works

By Matthew Tontonoz

Surprise! It has to do with metabolism.

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illustration of the p53 protein binding to a DNA helix

Finding

Sugar Directly Controls a Cancer-Causing Protein, Scientists Find

By Matthew Tontonoz

The discovery suggests a potential new treatment approach for certain cancers.

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An illustration of sugar pouring onto NRF2

In the Lab

Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype

By Matthew Tontonoz

Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found.

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MSK cancer researchers Elizabeth Adams, Charles Sawyers, and Rohit Bose

In The Lab

Ro Versus Musashi: How One Molecule Can Turn Cancer Cells Back to Normal

By Julie Grisham

Researchers identify a compound that appears to eliminate tumor cells in a dish and in mice.

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An illustration of a samurai and a crab.

Feature

Beyond Sugar: What Cancer Cells Need to Grow

By Matthew Tontonoz

While sugar gets most of the attention as a cancer fuel, other nutrients can be equally important.

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a cartoon of a cancer cell spooning glutamine from a jar

In the News

AACR 2019 Research Roundup: Pancreatic Cancer Immunotherapy, Prostate Cancer Drug Resistance, Insight into Inherited Cancer Mutations

By Jim Stallard Julie Grisham Matthew Tontonoz

Read up on the latest developments in several important areas of cancer research emerging from the 2019 American Association for Cancer Research annual meeting.

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AACR 2019 Annual Meeting

In The Lab

Starving Cancer Stem Cells Could Be the Trick to Treating Glioblastoma, Study Finds

By Julie Grisham Matthew Tontonoz

MSK researchers have identified a compound that kills glioblastoma cells using a mechanism that’s completely different from earlier treatments.

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Enhanced MRI of a glioblastoma

Finding

Research Uncovers the Genetic Causes of Aggressive Leukemia in Children

By Julie Grisham

Researchers have found that the genetic changes that cause pediatric leukemia are different from those that lead to leukemia in adults.

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Alex Kentsis in his lab

In The Clinic

There’s an App for That: When the Meaning of a BRCA Mutation Isn’t Clear-Cut

By Julie Grisham

A new project called the BRCA Exchange is sharing data about BRCA mutations and what they actually mean for cancer risk.

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Image of a mobile phone with a strand of DNA

In the Lab

Drugs That Stall — But Don’t Kill — Cancer Cells Are an Untapped Resource, Study Suggests

By Matthew Tontonoz

A drug combination that halts tumor cell division can stir the immune system into taking action.

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electron micrograph of a natural killer cell