Recent News: Cancer Genetics & Genomics

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70 News Items found
Finding
Section of a lung cancer tumor in mice
A Never-Before-Seen Cell State May Explain Cancer’s Ability to Resist Drugs

Identified in mice, this unusual cell state emerges early during tumor evolution and gives tumors enormous malleability.
In the Lab
CT scan showing lymphoma in the abdomen between the liver and the gallbladder.
A Metabolic Enzyme Drives Lymphoma and Is a Potential Drug Target

New research from Sloan Kettering Institute investigators pinpoints altered cell metabolism as a cause of B cell lymphoma.
In the Lab
Graphical representation of cells leaking into bloodstream
What Does Cancer Metastasis Have to Do with Wound Healing? More than You Might Think

Scientists are learning that — in a literal sense — metastasis is wound healing gone wrong.
Finding
Pedram Razavi, Jorge Reis-Filho, and Bob Li
Many Mutations Detected in Liquid Biopsy Tests Do Not Come from Cancer Cells, an MSK Study Finds

The new findings suggest the need for caution when interpreting the results from these tests.
In the Lab
illustration of the p53 protein binding to a DNA helix
New Findings Clarify How the “Guardian of the Genome” Works

Surprise! It has to do with metabolism.
Finding
An illustration of sugar pouring onto NRF2
Sugar Directly Controls a Cancer-Causing Protein, Scientists Find

The discovery suggests a potential new treatment approach for certain cancers.
In the Lab
MSK cancer researchers Elizabeth Adams, Charles Sawyers, and Rohit Bose
Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype

Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found.
In the Lab
An illustration of a samurai and a crab.
Ro Versus Musashi: How One Molecule Can Turn Cancer Cells Back to Normal

Researchers identify a compound that appears to eliminate tumor cells in a dish and in mice.
Feature
a cartoon of a cancer cell spooning glutamine from a jar
Beyond Sugar: What Cancer Cells Need to Grow

While sugar gets most of the attention as a cancer fuel, other nutrients can be equally important.
In the News
AACR 2019 Annual Meeting
AACR 2019 Research Roundup: Pancreatic Cancer Immunotherapy, Prostate Cancer Drug Resistance, Insight into Inherited Cancer Mutations

Read up on the latest developments in several important areas of cancer research emerging from the 2019 American Association for Cancer Research annual meeting.