Recent News: Cancer Genetics & Genomics

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69 News Items found
In the Lab
CT scan showing lymphoma in the abdomen between the liver and the gallbladder.
A Metabolic Enzyme Drives Lymphoma and Is a Potential Drug Target

By Matthew Tontonoz

New research from Sloan Kettering Institute investigators pinpoints altered cell metabolism as a cause of B cell lymphoma.
In the Lab
Graphical representation of cells leaking into bloodstream
What Does Cancer Metastasis Have to Do with Wound Healing? More than You Might Think

By Matthew Tontonoz

Scientists are learning that — in a literal sense — metastasis is wound healing gone wrong.
Finding
Pedram Razavi, Jorge Reis-Filho, and Bob Li
Many Mutations Detected in Liquid Biopsy Tests Do Not Come from Cancer Cells, an MSK Study Finds

By Matthew Tontonoz

The new findings suggest the need for caution when interpreting the results from these tests.
In the Lab
illustration of the p53 protein binding to a DNA helix
New Findings Clarify How the “Guardian of the Genome” Works

By Matthew Tontonoz

Surprise! It has to do with metabolism.
Finding
An illustration of sugar pouring onto NRF2
Sugar Directly Controls a Cancer-Causing Protein, Scientists Find

By Matthew Tontonoz

The discovery suggests a potential new treatment approach for certain cancers.
In the Lab
MSK cancer researchers Elizabeth Adams, Charles Sawyers, and Rohit Bose
Researchers Unravel the Biology of a Distinct Prostate Cancer Subtype

By Matthew Tontonoz

Mutations in a gene called FOXA1 are responsible for a distinct class of prostate cancer tumors, MSK researchers have found.
In the Lab
An illustration of a samurai and a crab.
Ro Versus Musashi: How One Molecule Can Turn Cancer Cells Back to Normal

By Julie Grisham

Researchers identify a compound that appears to eliminate tumor cells in a dish and in mice.
Feature
a cartoon of a cancer cell spooning glutamine from a jar
Beyond Sugar: What Cancer Cells Need to Grow

By Matthew Tontonoz

While sugar gets most of the attention as a cancer fuel, other nutrients can be equally important.
In the News
AACR 2019 Annual Meeting
AACR 2019 Research Roundup: Pancreatic Cancer Immunotherapy, Prostate Cancer Drug Resistance, Insight into Inherited Cancer Mutations

By Jim Stallard Julie Grisham Matthew Tontonoz

Read up on the latest developments in several important areas of cancer research emerging from the 2019 American Association for Cancer Research annual meeting.
In the Lab
Enhanced MRI of a glioblastoma
Starving Cancer Stem Cells Could Be the Trick to Treating Glioblastoma, Study Finds

By Julie Grisham Matthew Tontonoz

MSK researchers have identified a compound that kills glioblastoma cells using a mechanism that’s completely different from earlier treatments.