Faculty

Cell biologist Philipp Niethammer investigates tissue damage responses with advanced imaging approaches in zebrafish.

• PhD, European Molecular Biology Laboratories & Hamburg University, Germany

The Nikolov laboratory focuses on the structural, biophysical, and biochemical characterization of the molecular mechanisms of cell-cell interactions and signal transduction in the nervous system.

• PhD, The Rockefeller University

Systems biologist Thomas Norman develops new computational and functional genomics approaches for studying how genes interact to realize complex phenotypes.

• PhD, Harvard University

Physician-scientist Richard O'Reilly investigates the genetic disparities and cellular interactions between donor and host that affect allogeneic hematopoietic cell transplantation.

• MD, University of Rochester School of Medicine

Cancer geneticist Kenneth Offit focuses on gene characterization; genetic and epidemiologic studies of cancer-predisposing alleles; and the therapeutic, prognostic, and psychosocial translation of these findings.

• MD, Harvard Medical School

Alban Ordureau explores molecular signaling pathways that regulate cellular homeostasis, with a focus on the ubiquitin and autophagy systems.

• PhD, MRC-PPU - University of Dundee, Scotland, UK
• Post-doctoral training - Harvard Medical School, Boston

Cell biologist Michael Overholtzer studies the mechanisms of tumor initiation and progression, cell adhesion, and cell death.

• PhD, Princeton University

Molecular geneticist Elli Papaemmanouil performs systematic interrogations of well-annotated clinical trial cohorts in leukemia and cancer to explore how the compound genetic and clonal architecture in patients' leukemias and tumors dictate clinical phenotype, disease progression, and clinical outcomes.

• PhD – University of London, London, England, UK

Developmental biologist Luis F. Parada uses genetically engineered mouse models to study neurofibromatosis, brain tumors, cancer stem cells, and tumor progression.

• PhD, Massachusetts Institute of Technology

The Patel laboratory studies the structural biology of macromolecular recognition, regulation and catalysis. Ongoing projects include structure-function studies of the CRISPR-Cas and cGAS-STING surveillance pathways, on the role of Structure Maintenance Chromosome complexes in mediating DNA double strand break repair, on the role of histone and DNA methylation in epigenetic regulation and on RNA-mediated processes ranging from riboswitches and ribozymes to those governing siRNA and piRNA pathways.

• PhD, New York University