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New Milestones in Cancer Research and Education at Memorial Sloan-Kettering Cancer Center

The Mortimer B. Zuckerman Research Center
The Mortimer B. Zuckerman Research Center
The Mortimer B. Zuckerman Research Center
NEW YORK, September 2006 - Memorial Sloan-Kettering Cancer Center (MSKCC) is now poised to take greater advantage of a new era in cancer research and education with the opening of a state-of-the-art research center, the establishment of a new graduate school, and the founding of a novel research program in human oncology.

These major developments in the pursuit of innovative cancer research and education were celebrated with a trilogy of events from September 19 - 21, 2006 at MSKCC.

"Achieving the medical promise of cancer research requires a deeper understanding of the biology of cancer and imaginative application of new knowledge in the clinic," said MSKCC President Harold Varmus. "The expansion of our research and educational programs to better understand the genetic and biochemical mechanisms by which cancers arise and behave will lead to improvements in detecting, classifying, monitoring, and treating cancer."

Memorial Sloan-Kettering has nearly doubled the size of its research enterprise with the official opening of a new research complex, named in recognition of a $100 million gift from Memorial Sloan-Kettering Boards member Mortimer B. Zuckerman - the single largest commitment by an individual in the Center's history.

The first new research facility for MSKCC since 1989, The Mortimer B. Zuckerman Research Center's 23-story building is uniquely designed to provide basic scientists and clinical investigators with an inspiring, interactive, and efficient environment in which they can work together. A second phase of construction is now underway to build a connecting seven-story structure. One of the tallest laboratory buildings in the world, the 693,000 total-square-foot research complex will cost an estimated $503 million.

A three-day celebration of public lectures ended with an open house at the Zuckerman Research Center on September 21 not only recognized the official opening of the new research facility, but also celebrates the inaugural class of the Louis V. Gerstner, Jr. Sloan-Kettering Graduate School of Biomedical Sciences, and acknowledges the establishment a novel research program in human oncology, the Human Oncology and Pathogenesis Program (HOPP).

The new graduate school offers a novel doctoral program that trains basic laboratory scientists to work in research areas directly applicable to human disease and, in particular, cancer. HOPP is a major hospital-based initiative in which scientists and physicians aim to translate laboratory findings into novel approaches to cancer detection, diagnosis, treatment, and prevention.

Both of these programs are housed in The Mortimer B. Zuckerman Research Center, located across the street from Memorial Hospital.The proximity encourages interdisciplinary efforts as scientists and physicians work in concert to achieve a better understanding of cancer and develop new, more effective ways of controlling the disease.

A Laboratory in the Zuckerman Research Center
A Laboratory in the Zuckerman Research Center
A Laboratory in the Zuckerman Research Center
The 23-story portion of the facility includes 16 floors of state-of-the-art laboratories that are configured to foster interactions important to productive collaborations among basic scientists and clinical investigators from different disciplines.These floors incorporate an open, "modular" laboratory design that provides the ability to customize and reconfigure each area based on the evolving needs of the investigators. Generous nine-and-a-half-foot-high ceilings on each laboratory floor also allow for flexibility in equipping those areas.

These laboratories will accommodate the Center's programs inimmunology, molecular pharmacology and chemistry, and cancer biology and genetics. The facility will also include shared core laboratory facilities such as high-through put drug screening to identify small-molecule drug candidates and nuclear magnetic resonance that will provide crucial equipment and technical support for work conducted by multiple programs. The connecting seven-story structure will add a conference center with a 350-seat auditorium and a number of "dry" laboratories, including space for computational biology.

The research facility features a strong emphasis on energy-efficiency and environmental sustainability and it is expected to be among the first research buildings in New York State to receive certification from the Leadership in Energy and Environmental Design (LEED®) GreenBuilding Rating System™, a benchmarking standard developed by the U.S. Green Building Council that evaluates the environmental performance of buildings. LEED® certification recognizes aconstruction approach that optimizes environmental and economic factors such as water savings, energy efficiency, materials selection, and indoor environmental quality.

Designed by Skidmore, Owings & Merrill LLP in collaborationwith the Zimmer Gunsul Frasca Partnership, the facility was built byTurner Construction Company under the direction of MemorialSloan-Kettering's Facilities Management. Construction began with the groundbreaking in the spring of 2002 and the first occupants moved into the building in May 2006.

Interaction Staircase
Interaction Staircase
Interaction Staircase
Original, permanent art installations are also a unique feature of the design of the facility. They include imagery in the glass of the "interaction staircase" (centrally located and designed to encourage exchanges and chance encounters among researchers throughout the 23-story building) featuring mirrored surfaces and silk-screened glass; a distinctive "sculptural ceiling" in the Cyber Lounge (a central gathering place for researchers and students); and other commissioned artwork for the connecting seven-story structure in what will become the permanent lobby of the research center.



The research complex will accommodate approximately 100 researchers and their growing teams—providing 16 floors that house many of the Center's laboratories and offers the space needed for the recruitment of 68 new investigators and the expansion of a number of existing programs within the Sloan-Kettering Institute.
The 23-story complex is the first new research building built by Memorial Sloan-Kettering Cancer Center since 1989. Capitalizing on new opportunities in cancer research, the facility is intended to provide basic scientists and clinical researchers with an inspiring, interactive, and efficient environment in which they can work together.
The Mortimer B. Zuckerman Research Center is a high-performance "green building," which strives to address environmental, economic, and social concerns by using design and construction practices intended to significantly reduce or eliminate negative effects on the environment and the building's occupants.
Memorial Sloan-Kettering Cancer Center selected several artists to create original, permanent art installations in the design of the Mortimer B. Zuckerman Research Center. Their work underscores the connection between art and architecture, form and function.
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©2008 Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences,
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